Psychiatric University Hospital, University of Zurich, Zurich, Switzerland.
Addiction. 2009 Aug;104(8):1411-9. doi: 10.1111/j.1360-0443.2009.02640.x.
To examine the strength of association between smoking and mood disorders and the association between smoking and its traditional risk factors, comparing those who started smoking in adolescence with those who started smoking in early adulthood.
The analyses relied on prospective data from the Zurich Study. This longitudinal community study started in 1979 with a stratified sample of 591 participants aged 20/21 years, weighted towards those with mental disorders. Follow-up interviews were conducted at ages 23, 28, 30, 35 and 41.
In this analysis the adult versus adolescent onset of smoking was regressed on the cumulative prevalence of mood disorders, personality characteristics measured by the Freiburg Personality Inventory, common risk factors such as parental smoking, conduct and school problems, troubles with the family and basic socio-demographic variables (sex, education).
In the Zurich Study cohort we found that 61.6% were former or current smokers, of whom 87% started smoking before the age of 20 and 13% after the age of 20. Adolescent onset of smoking was associated strongly with later major depression, dysthymia or bipolar disorders and, furthermore, with parental smoking, extroverted personality and discipline problems and rebelliousness in youth. However, only depression and dysthymia were associated with adult onset smoking and other risk factors associated with smoking were not so associated in this group.
Correlates of smoking onset in adolescence are mainly not applicable to the onset of smoking in young adulthood. Smoking onset beyond adolescence is an open research issue.
研究青少年期和成年早期开始吸烟与心境障碍之间的关联强度,以及吸烟与传统危险因素之间的关联,并对两者进行比较。
该分析依赖于苏黎世研究的前瞻性数据。这项纵向社区研究始于 1979 年,对 591 名 20/21 岁的具有精神障碍的分层参与者进行了加权调查。在 23、28、30、35 和 41 岁时进行了随访访谈。
在本分析中,将吸烟的成人期与青少年期发病情况回归为心境障碍的累积患病率、由弗莱堡人格量表测量的人格特征、常见危险因素(如父母吸烟、行为和学业问题、家庭问题和基本社会人口统计学变量(性别、教育)。
在苏黎世研究队列中,我们发现 61.6%的参与者是曾经或现在的吸烟者,其中 87%的人在 20 岁之前开始吸烟,13%的人在 20 岁之后开始吸烟。青少年期开始吸烟与后来的重度抑郁症、心境恶劣或双相障碍强烈相关,此外,还与父母吸烟、外向性格和青年时期的纪律问题和叛逆行为有关。然而,只有抑郁和心境恶劣与成年期开始吸烟有关,而与吸烟相关的其他危险因素在该组中没有如此相关。
青少年期吸烟发病的相关因素主要不适用于成年早期吸烟发病。青春期后开始吸烟是一个开放的研究问题。