Department of Epidemiology, University of North Carolina, Chapel Hill, 27599, USA.
Int J Cancer. 2010 Jan 15;126(2):572-7. doi: 10.1002/ijc.24770.
Human papillomavirus (HPV) prevalence was estimated from 2,705 sexually active, uncircumcised, human immunodeficiency virus seronegative men aged 17-28 years in Kisumu, Kenya. HPV prevalence was 51.1% (95% confidence interval: 49.2-53.0%) in penile cells from the glans/coronal sulcus and/or shaft. HPV prevalence varied by anatomical site, with 46.5% positivity in the glans/coronal sulcus compared with 19.1% in the shaft (p < 0.0001). High-risk HPV was detected in 31.2% of glans and 12.3% of shaft samples (p < 0.0001). HPV16 was the most common type and 29.2% of men were infected with more than one HPV type. Risk factors for HPV infection included presence of C. trachomatis, N. gonorrhea, self-reported sexually transmitted infections, and less frequent bathing. Lifetime number of sexual partners and herpes simplex virus type-2 seropositivity were also marginally associated with HPV infection.
人乳头瘤病毒（HPV）流行率从肯尼亚基苏木的 2705 名性活跃、未割礼、人类免疫缺陷病毒血清阴性的 17-28 岁男性中估计得出。龟头/冠状沟和/或阴茎杆细胞的 HPV 流行率为 51.1%（95%置信区间：49.2-53.0%）。HPV 流行率按解剖部位不同而有所差异，龟头/冠状沟处的阳性率为 46.5%，而阴茎杆处为 19.1%（p<0.0001）。在龟头样本中检测到高危 HPV 的占 31.2%，在阴茎杆样本中占 12.3%（p<0.0001）。HPV16 是最常见的类型，29.2%的男性感染了一种以上的 HPV 类型。HPV 感染的危险因素包括沙眼衣原体、淋病奈瑟菌、自述的性传播感染，以及洗澡频率较低。性伴侣终身数量和单纯疱疹病毒 2 型血清阳性也与 HPV 感染有一定的关联。
