Physical Therapy Department, Brazilian National Cancer Institute-INCA, Rua do Rezende 128, Centro-Rio de Janeiro, RJ 20231-092, Brazil.
Support Care Cancer. 2010 Apr;18(4):481-90. doi: 10.1007/s00520-009-0697-0. Epub 2009 Jul 23.
The purpose of this study was to validate the Portuguese version of the Functional Assessment of Cancer Therapy-Fatigue (FACT-F) in order to establish its assessment properties, including validity and reliability in a sample of Brazilian cancer patients.
Two hundred seventy patients with different types of cancer were included for this study; the mean age was 50.5 years. The reliability was assessed by internal consistency and reproducibility. Construct validity was assessed through convergent validity and discriminant validity. Convergent validity was examined by comparing the FACT-F to the SF-36. Discriminant validity of the FACT-F evaluated the ability of the scale to differentiate defined groups, discriminating patients according to Eastern Cooperative Oncology Group Performance Status and different stages of disease.
FACT-F had high internal consistency (Cronbach alpha coefficient was 0.78 for physical well-being, 0.68 for social/family well-being, 0.75 for emotional well-being, 0.74 for functional well-being, 0.91 for fatigue, and 0.92 for total FACT-F). The range of test-retest intraclass correlation was from 0.72 to 0.91 (p < 0.0001). The Pearson product correlation revealed good correlations between the total FACT-F and subscales of the SF-36 in most dimensions, ranging from r = 0.51 to r = 0.76, except for SF-36 physical (r = 0.31). The positive correlations between the SF-36 vitality scale and FACT-F total (r = 0.76) and the fatigue subscale (r = 0.77) support the convergent validity.
The Portuguese version of FACT-F is a reliable and valid instrument to assess quality of life and fatigue, representing a valid tool to screen cancer-related fatigue in Brazilian cancer patients.
本研究旨在验证葡萄牙文版功能性评估癌症治疗疲劳量表（FACT-F）的有效性，以确定其在巴西癌症患者样本中的评估特性，包括有效性和可靠性。
本研究共纳入 270 名患有不同类型癌症的患者，平均年龄为 50.5 岁。通过内部一致性和可重复性评估可靠性。通过收敛有效性和判别有效性评估结构有效性。通过将 FACT-F 与 SF-36 进行比较来检验收敛有效性。通过评估量表区分特定组别的能力，即根据东部合作肿瘤学组表现状态和疾病的不同阶段区分患者，来评估 FACT-F 的判别有效性。
FACT-F 具有较高的内部一致性（身体状况的 Cronbach α 系数为 0.78，社会/家庭状况为 0.68，情感状况为 0.75，功能状况为 0.74，疲劳为 0.91，总 FACT-F 为 0.92）。测试-重测的组内相关系数范围为 0.72 至 0.91（p<0.0001）。Pearson 乘积相关显示，在大多数维度上，总 FACT-F 与 SF-36 子量表之间存在良好的相关性，范围从 r=0.51 到 r=0.76，除了 SF-36 身体（r=0.31）。SF-36 活力量表与 FACT-F 总分（r=0.76）和疲劳子量表（r=0.77）之间的正相关支持收敛有效性。
葡萄牙文版 FACT-F 是一种可靠且有效的评估生活质量和疲劳的工具，是巴西癌症患者筛查癌症相关疲劳的有效工具。
