Thyssen Jacob Pontoppidan, Menné Torkil, Johansen Jeanne Duus
National Allergy Research Centre, Department of Dermato-Allergology, Gentofte Hospital, University of Copenhagen, 2900Hellerup, Denmark.
Sci Total Environ. 2009 Oct 1;407(20):5315-8. doi: 10.1016/j.scitotenv.2009.06.034. Epub 2009 Jul 24.
Nickel allergic subjects are at risk factor of acquiring hand eczema. In 1990 and 1994, respectively, Denmark and member states in the EU regulated nickel release from selected consumer products. The intention was that the nickel epidemic could be controlled and prevented if the general population was protected from high cutaneous nickel concentrations. Despite a decrease, the prevalence of nickel allergy remains high as nearly 10% of young women are nickel allergic.
This study aimed to perform dimethylglyoxime (DMG) testing of inexpensive jewelry and hair clasps purchased from random stores in Copenhagen, Denmark to detect the proportion of items that may result in nickel allergy.
Inexpensive jewelry and hair clasps were purchased from 36 stores and street vendors in Copenhagen and were later tested for nickel release using the DMG test.
The study showed that 19.3% hair clasps, 14.8% earrings, and 12.9% necklaces intended for adult women released an excessive amount of nickel. Of 25 stores visited, 36.0% sold DMG positive jewelry. For items designed for children, excessive nickel release was identified in hair clasps (79.4%) and in finger rings (20%). Four (50.0%) of 8 children clothing stores sold jewelry that released too much nickel.
Excessive nickel release has been regulated since 1990 in Denmark. However, 1/5 of purchased items released nickel in concentrations that may lead to nickel allergy. Especially hair clasps intended for children released an excessive amount of nickel.
镍过敏者有患手部湿疹的风险因素。丹麦和欧盟成员国分别于1990年和1994年对特定消费品的镍释放量进行了监管。目的是如果普通人群能免受高皮肤镍浓度的影响，镍流行情况就能得到控制和预防。尽管有所下降，但镍过敏的患病率仍然很高，近10%的年轻女性对镍过敏。
本研究旨在对从丹麦哥本哈根随机商店购买的廉价珠宝和发夹进行丁二酮肟（DMG）测试，以检测可能导致镍过敏的物品比例。
从哥本哈根的36家商店和街头小贩处购买廉价珠宝和发夹，随后使用DMG测试对其镍释放量进行检测。
研究表明，面向成年女性的发夹中有19.3%、耳环中有14.8%、项链中有12.9%释放出过量镍。在所走访的25家商店中，36.0%出售DMG呈阳性的珠宝。对于儿童用品，发夹（79.4%）和戒指（20%）中发现有过量镍释放。8家儿童服装店中有4家（50.0%）出售镍释放量过高的珠宝。
自1990年以来，丹麦已对过量镍释放进行了监管。然而，所购买物品中有五分之一释放的镍浓度可能导致镍过敏。尤其是儿童发夹释放出过量的镍。
