Agence Française de Sécurité Sanitaire des Aliments, Unité Epidémiologie, Lyon cedex 07, France.
Vet J. 2010 Sep;185(3):338-40. doi: 10.1016/j.tvjl.2009.06.019. Epub 2009 Jul 26.
The occurrence of secondary cases of atypical and classical scrapie was examined in 340 outbreaks of atypical and 296 of classical sheep scrapie detected in France during active surveillance programmes between 2002 and 2007. The prevalence of atypical scrapie in these flocks was 0.05% under selective culling and 0.07% under intensified monitoring i.e. not significantly different from that detected during active surveillance of the general population (P>0.5), whereas these figures were much higher for classical scrapie (3.67% and 0.25%, respectively, P<10(-5)). In addition the number of atypical scrapie cases per outbreak did not indicate clustering. The results suggest that atypical scrapie occurs spontaneously or is not particularly contagious, and that the control measures in force allowed appropriate control of classical scrapie but were not more efficient than active surveillance in detecting cases of atypical scrapie.
在 2002 年至 2007 年期间进行的主动监测计划中，检查了在法国检测到的 340 起非典型和 296 起经典绵羊痒病爆发中二次发生非典型和经典痒病的情况。在选择性淘汰下，这些羊群中非典型痒病的流行率为 0.05%，在强化监测下（即没有显著不同于一般人群的主动监测（P>0.5），而这些数字对于经典痒病则要高得多（分别为 3.67%和 0.25%，P<10（-5））。此外，每次爆发的非典型痒病病例数并未表明聚类。结果表明，非典型痒病是自发发生的，或者不是特别具有传染性的，并且现行的控制措施允许对经典痒病进行适当的控制，但在检测非典型痒病病例方面并不比主动监测更有效。
