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2
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Lancet. 2007 Jun 9;369(9577):1961-71. doi: 10.1016/S0140-6736(07)60917-9.
3
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Med Mycol. 2007 May;45(3):221-4. doi: 10.1080/13693780601164298.
4
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Antimicrob Agents Chemother. 2004 Feb;48(2):384-7. doi: 10.1128/AAC.48.2.384-387.2004.
5
Genetic susceptibility to vaginal candidiasis.阴道念珠菌病的遗传易感性。
Med Mycol. 2003 Apr;41(2):143-7. doi: 10.1080/mmy.41.2.143.147.
6
In vitro susceptibilities of Malassezia species to a new triazole, albaconazole (UR-9825), and other antifungal compounds.马拉色菌属对新型三唑类药物阿巴康唑（UR-9825）及其他抗真菌化合物的体外敏感性
Antimicrob Agents Chemother. 2003 Jul;47(7):2342-4. doi: 10.1128/AAC.47.7.2342-2344.2003.
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In vitro antifungal activities of the new triazole UR-9825 against clinically important filamentous fungi.新型三唑类药物UR-9825对临床重要丝状真菌的体外抗真菌活性。
Antimicrob Agents Chemother. 2001 Sep;45(9):2635-7. doi: 10.1128/AAC.45.9.2635-2637.2001.
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In-vitro comparative activity of UR-9825, itraconazole and fluconazole against clinical isolates of Candida spp.UR-9825、伊曲康唑和氟康唑对念珠菌属临床分离株的体外比较活性
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在阴道炎模型中阿巴康唑对白色念珠菌的疗效。

Efficacy of albaconazole against Candida albicans in a vaginitis model.

作者信息

González Gloria M, Robledo Efrén, Garza-González Elvira, Elizondo Mariana, González J Gerardo

机构信息

Departamento de Microbiología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.

出版信息

Antimicrob Agents Chemother. 2009 Oct;53(10):4540-1. doi: 10.1128/AAC.00565-09. Epub 2009 Jul 27.

DOI:10.1128/AAC.00565-09
PMID:19635949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2764185/
Abstract

The efficacy of albaconazole (ABC) was evaluated using a murine model of vaginal Candida albicans infection. Both ABC and fluconazole (FLC) were effective in reducing the fungal load from vaginas of infected mice; however, ABC demonstrated encouraging activities against an FLC-resistant strain, with trends toward superiority over FLC in some treatment groups.

摘要

使用白色念珠菌阴道感染小鼠模型评估了阿巴康唑（ABC）的疗效。ABC和氟康唑（FLC）均可有效降低感染小鼠阴道中的真菌载量；然而，ABC对氟康唑耐药菌株表现出令人鼓舞的活性，在某些治疗组中显示出优于氟康唑的趋势。