基于解剖图谱的脑激活弥散光学层析成像。
Anatomical atlas-guided diffuse optical tomography of brain activation.
机构信息
Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
出版信息
Neuroimage. 2010 Jan 1;49(1):561-7. doi: 10.1016/j.neuroimage.2009.07.033. Epub 2009 Jul 28.
Abstract
We describe a neuroimaging protocol that utilizes an anatomical atlas of the human head to guide diffuse optical tomography of human brain activation. The protocol is demonstrated by imaging the hemodynamic response to median-nerve stimulation in three healthy subjects, and comparing the images obtained using a head atlas with the images obtained using the subject-specific head anatomy. The results indicate that using the head atlas anatomy it is possible to reconstruct the location of the brain activation to the expected gyrus of the brain, in agreement with the results obtained with the subject-specific head anatomy. The benefits of this novel method derive from eliminating the need for subject-specific head anatomy and thus obviating the need for a subject-specific MRI to improve the anatomical interpretation of diffuse optical tomography images of brain activation.
摘要
我们描述了一种利用人类头部解剖图谱指导人类大脑激活弥散光学断层扫描的神经影像学方法。该方案通过对 3 名健康受试者的正中神经刺激后的血流动力学反应进行成像，并将使用头部图谱获得的图像与使用受试者特定头部解剖结构获得的图像进行比较，从而得到了验证。结果表明，使用头部图谱解剖结构可以将大脑激活的位置重建到预期的大脑脑回，这与使用受试者特定头部解剖结构获得的结果一致。这种新方法的优点在于消除了对受试者特定头部解剖结构的需求，从而避免了使用受试者特定的 MRI 来改善大脑激活弥散光学断层扫描图像的解剖学解释的需要。
相似文献
1
Anatomical atlas-guided diffuse optical tomography of brain activation.基于解剖图谱的脑激活弥散光学层析成像。
Neuroimage. 2010 Jan 1;49(1):561-7. doi: 10.1016/j.neuroimage.2009.07.033. Epub 2009 Jul 28.
2
Depth-compensated diffuse optical tomography enhanced by general linear model analysis and an anatomical atlas of human head.基于广义线性模型分析和人体头部解剖图谱的深度补偿漫射光学断层成像增强。
Neuroimage. 2014 Jan 15;85 Pt 1(0 1):166-80. doi: 10.1016/j.neuroimage.2013.07.016. Epub 2013 Jul 14.
3
Atlas-based head modeling and spatial normalization for high-density diffuse optical tomography: in vivo validation against fMRI.基于图谱的头部建模和高密度扩散光学断层成像的空间标准化：与 fMRI 的体内验证。
Neuroimage. 2014 Jan 15;85 Pt 1(0 1):117-26. doi: 10.1016/j.neuroimage.2013.03.069. Epub 2013 Apr 8.
4
Validating atlas-guided DOT: a comparison of diffuse optical tomography informed by atlas and subject-specific anatomies.验证图谱引导的 DOT：基于图谱和个体特定解剖结构的弥散光学层析成像的比较。
Neuroimage. 2012 Sep;62(3):1999-2006. doi: 10.1016/j.neuroimage.2012.05.031. Epub 2012 May 23.
5
Atlas-guided volumetric diffuse optical tomography enhanced by generalized linear model analysis to image risk decision-making responses in young adults.通过广义线性模型分析增强的图谱引导体积扩散光学断层扫描，用于对年轻人的风险决策反应进行成像。
Hum Brain Mapp. 2014 Aug;35(8):4249-66. doi: 10.1002/hbm.22459. Epub 2014 Mar 12.
6
Effects of atlas-based anatomy on modelled light transport in the neonatal head.基于寰枢椎解剖结构的模型对新生儿头部光传输的影响。
Phys Med Biol. 2023 Jul 3;68(13):135019. doi: 10.1088/1361-6560/acd48c.
7
Interleaved imaging of cerebral hemodynamics and blood flow index to monitor ischemic stroke and treatment in rat by volumetric diffuse optical tomography.容积式漫射光学断层成像监测大鼠脑血流动力学和血流指数变化及其对缺血性脑卒中的治疗作用
Neuroimage. 2014 Jan 15;85 Pt 1(0 1):566-82. doi: 10.1016/j.neuroimage.2013.07.020. Epub 2013 Jul 16.
8
Multi-atlas segmentation of the whole hippocampus and subfields using multiple automatically generated templates.使用多个自动生成的模板对整个海马体及其子区进行多图谱分割。
Neuroimage. 2014 Nov 1;101:494-512. doi: 10.1016/j.neuroimage.2014.04.054. Epub 2014 Apr 29.
9
Improved EEG source analysis using low-resolution conductivity estimation in a four-compartment finite element head model.在四室有限元头部模型中使用低分辨率电导率估计改进脑电图源分析。
Hum Brain Mapp. 2009 Sep;30(9):2862-78. doi: 10.1002/hbm.20714.
10
A 4D neonatal head model for diffuse optical imaging of pre-term to term infants.一种用于早产儿至足月儿漫射光学成像的四维新生儿头部模型。
Neuroimage. 2014 Oct 15;100:385-94. doi: 10.1016/j.neuroimage.2014.06.028. Epub 2014 Jun 18.
引用本文的文献
1
Emerging panorama of functional near-infrared spectroscopy in Latin America.拉丁美洲功能性近红外光谱学的新全景。
Neurophotonics. 2026 Jan;13(Suppl 1):S13002. doi: 10.1117/1.NPh.13.S1.S13002. Epub 2025 Sep 12.
2
High-density multidistance fNIRS enhances detection of brain activity during a word-color Stroop task.高密度多距离功能近红外光谱技术可增强对词语-颜色斯特鲁普任务期间大脑活动的检测。
Neurophotonics. 2025 Jul;12(3):035010. doi: 10.1117/1.NPh.12.3.035010. Epub 2025 Sep 2.
3
Robust photogrammetric scalp morphology estimation for functional optical neuroimaging.用于功能性光学神经成像的稳健摄影测量头皮形态估计
Neurophotonics. 2025 Jul;12(3):035002. doi: 10.1117/1.NPh.12.3.035002. Epub 2025 Jul 28.
4
Simultaneously Acquired Magnetoencephalography and Diffuse Optical Tomography Data Reveals Correlated Somatosensory Activity.同时采集的脑磁图和扩散光学断层扫描数据揭示了相关的体感活动。
Hum Brain Mapp. 2025 Aug 1;46(11):e70293. doi: 10.1002/hbm.70293.
5
Continuous Wave-Diffuse Optical Tomography (CW-DOT) in Human Brain Mapping: A Review.人脑图谱中的连续波-扩散光学断层扫描（CW-DOT）综述
Sensors (Basel). 2025 Mar 25;25(7):2040. doi: 10.3390/s25072040.
6
High-Density Multi-Distance fNIRS Enhances Detection of Brain Activity during a Word-Color Stroop Task.高密度多距离功能近红外光谱技术增强了对词语-颜色斯特鲁普任务中大脑活动的检测。
bioRxiv. 2025 Mar 14:2025.03.12.642917. doi: 10.1101/2025.03.12.642917.
7
Diffuse optical tomography of the brain: effects of inaccurate baseline optical parameters and refinements using learned post-processing.大脑的扩散光学断层扫描：不准确的基线光学参数的影响以及使用学习后处理的改进
Biomed Opt Express. 2024 Jul 5;15(8):4470-4485. doi: 10.1364/BOE.524245. eCollection 2024 Aug 1.
8
Subject-specific information enhances spatial accuracy of high-density diffuse optical tomography.特定受试者信息可提高高密度扩散光学断层扫描的空间准确性。
Front Neuroergon. 2024 Feb 19;5:1283290. doi: 10.3389/fnrgo.2024.1283290. eCollection 2024.
9
Short-separation regression incorporated diffuse optical tomography image reconstruction modeling for high-density functional near-infrared spectroscopy.短间距回归结合漫射光学层析成像用于高密度功能近红外光谱的图像重建建模
Neurophotonics. 2023 Apr;10(2):025007. doi: 10.1117/1.NPh.10.2.025007. Epub 2023 May 23.
10
Effects of atlas-based anatomy on modelled light transport in the neonatal head.基于寰枢椎解剖结构的模型对新生儿头部光传输的影响。
Phys Med Biol. 2023 Jul 3;68(13):135019. doi: 10.1088/1361-6560/acd48c.
本文引用的文献
1
Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head.用于光子在包括成人头部在内的复杂非均匀介质中迁移的三维蒙特卡罗代码。
Opt Express. 2002 Feb 11;10(3):159-70. doi: 10.1364/oe.10.000159.
2
Three-dimensional optical tomography of hemodynamics in the human head.人体头部血流动力学的三维光学断层扫描
Opt Express. 2001 Sep 10;9(6):272-86. doi: 10.1364/oe.9.000272.
3
Human brain mapping: hemodynamic response and electrophysiology.人类脑图谱：血液动力学反应与电生理学
Clin Neurophysiol. 2008 Apr;119(4):731-43. doi: 10.1016/j.clinph.2007.10.026. Epub 2008 Jan 9.
4
Retinotopic mapping of adult human visual cortex with high-density diffuse optical tomography.利用高密度扩散光学断层扫描对成人人脑视觉皮层进行视网膜拓扑映射。
Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12169-74. doi: 10.1073/pnas.0611266104. Epub 2007 Jul 6.
5
Functional near infrared spectroscopy (fNIRS): an emerging neuroimaging technology with important applications for the study of brain disorders.功能近红外光谱技术（fNIRS）：一种新兴的神经成像技术，在脑疾病研究中具有重要应用。
Clin Neuropsychol. 2007 Jan;21(1):9-37. doi: 10.1080/13854040600910018.
6
10/20, 10/10, and 10/5 systems revisited: their validity as relative head-surface-based positioning systems.重新审视10/20、10/10和10/5系统：它们作为基于头部表面的相对定位系统的有效性。
Neuroimage. 2007 Feb 15;34(4):1600-11. doi: 10.1016/j.neuroimage.2006.09.024. Epub 2007 Jan 4.
7
A spatial and temporal comparison of hemodynamic signals measured using optical and functional magnetic resonance imaging during activation in the human primary visual cortex.在人类初级视觉皮层激活期间，使用光学和功能磁共振成像测量的血流动力学信号的时空比较。
Neuroimage. 2007 Feb 1;34(3):1136-48. doi: 10.1016/j.neuroimage.2006.08.048. Epub 2006 Nov 28.
8
Cortical brain responses during passive nonpainful median nerve stimulation at low frequencies (0.5-4 Hz): an fMRI study.低频（0.5 - 4赫兹）下被动非疼痛性正中神经刺激期间的大脑皮质反应：一项功能磁共振成像研究
Hum Brain Mapp. 2007 Jul;28(7):645-53. doi: 10.1002/hbm.20292.
9
Somatotopy of anterior cingulate cortex (ACC) and supplementary motor area (SMA) for electric stimulation of the median and tibial nerves: an fMRI study.前扣带回皮质（ACC）和辅助运动区（SMA）对正中神经和胫神经电刺激的躯体定位：一项功能磁共振成像研究。
Neuroimage. 2006 Nov 1;33(2):700-5. doi: 10.1016/j.neuroimage.2006.06.030. Epub 2006 Aug 28.
10
Sensorimotor cortex localization: comparison of magnetoencephalography, functional MR imaging, and intraoperative cortical mapping.感觉运动皮层定位：脑磁图、功能磁共振成像与术中皮层图谱的比较
Radiology. 2006 Oct;241(1):213-22. doi: 10.1148/radiol.2411050796. Epub 2006 Aug 14.
Zotero 插件