肥大细胞发育和成熟的分子调控。
Molecular regulation of mast cell development and maturation.
机构信息
Allergy and Immunology Institute, School of Medicine, Shenzhen University, Shenzhen, China.
出版信息
Mol Biol Rep. 2010 Apr;37(4):1993-2001. doi: 10.1007/s11033-009-9650-z. Epub 2009 Jul 31.
PMID:19644767
Abstract
Mast cells play a crucial role in the pathogenesis of allergic diseases. In recent years, tremendous progresses have been made in studies of mast cell origination, migration, proliferation, maturation and survival, and the cytokines regulating these activities. These advances have significantly improved our understandings to mast cell biology and to the molecular mechanisms of mast cells in the pathogenesis of allergic diseases.
摘要
肥大细胞在过敏性疾病的发病机制中起着至关重要的作用。近年来，在肥大细胞起源、迁移、增殖、成熟和存活以及调节这些活动的细胞因子的研究方面取得了巨大进展。这些进展显著提高了我们对肥大细胞生物学以及肥大细胞在过敏性疾病发病机制中的分子机制的理解。
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