[高茎橐吾化学成分的研究]
[Studies on chemical constituents of Ligularia altaica].
作者信息
Zhang Chao-Feng, Wang Qiong, Zhang Mian
机构信息
Key Laboratory of Modern Chinese Medicines of Ministry of Education/Research Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China.
出版信息
Zhong Yao Cai. 2009 Apr;32(4):524-6.
OBJECTIVE
To study the chemical constituents of Lighularia altaica.
METHODS
Various chromatographic techniques were used to isolate and purify the chemical compounds, their structure were elucidated by means of mass, physico-chemical properties and NMR spectral data.
RESULTS
Nine compounds were obtained as: lupeol (1), oleanolic acid (2), 3beta, 16beta-dihydroxy-12-oleanen-28-al (3), ergosterol peroxide (4), stigmasta-7-en-ol (5), 11-hydroxy-10,11-dihydro-euparin (6), 5-hydroxybenzofuran-2(3H) -one- (7), except for beta-sitosterol (8) and daucostrol (9).
CONCLUSION
Compounds 3 - 7 are isolated for the first time from this genus, the other compounds are obtained from this plant for the first time.
目的
研究高叶橐吾的化学成分。
方法
采用多种色谱技术分离纯化化合物，通过质谱、理化性质和核磁共振光谱数据对其结构进行鉴定。
结果
得到9种化合物，分别为羽扇豆醇（1）、齐墩果酸（2）、3β,16β - 二羟基 - 12 - 齐墩烯 - 28 - 醛（3）、过氧化麦角甾醇（4）、豆甾 - 7 - 烯醇（5）、11 - 羟基 - 10,11 - 二氢 - 欧前胡素（6）、5 - 羟基苯并呋喃 - 2(3H)-酮（7），以及β - 谷甾醇（8）和胡萝卜苷（9）。
结论
化合物3 - 7首次从该属植物中分离得到，其他化合物首次从该植物中获得。
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