Medical Electronic Engineering Department, Fourth Military Medical University, Xi'an, 710032, China.
Med Biol Eng Comput. 2009 Oct;47(10):1045-52. doi: 10.1007/s11517-009-0516-2. Epub 2009 Aug 5.
The high false-positive rate in clinical examinations limits the application of electrical impedance scanning (EIS) on breast cancer detection. One of the reasons is the non-uniform electrode-skin interface, which induces the 'contact artifact' in the results. To decrease the 'contact artifact', we designed a novel disposable electrode-skin interface [cotton fine grid thin layer (CFGTL)-interface], which is 0.2-mm thick and has a conductivity similar to that of normal breast tissue. The performance of the CFGTL-interface was evaluated by comparing it with the ultrasound gel interface generally used in EIS examinations. The test was conducted on 50 healthy female volunteers using two different interfaces separately, and a paired comparison method was used to analyze the effect of the CFGTL-interface on EIS measuring data. The results showed that the CFGTL-interface could effectively decrease the variation and the range of data fluctuation, which suggested that CFGTL-interface can decrease the 'contact artifact' and increase the accuracy of the examination. The CFGTL-interface appears to be an effective electrode-skin interface for breast EIS examination.
临床检查中的高假阳性率限制了电阻抗扫描 (EIS) 在乳腺癌检测中的应用。其中一个原因是电极-皮肤界面不均匀，这会在结果中产生“接触伪影”。为了减少“接触伪影”，我们设计了一种新型的一次性电极-皮肤界面[棉细网格薄层 (CFGTL)-界面]，其厚度为 0.2 毫米，电导率与正常乳房组织相似。通过将其与 EIS 检查中通常使用的超声凝胶界面进行比较，评估了 CFGTL-界面的性能。该测试在 50 名健康女性志愿者中进行，分别使用两种不同的界面，采用配对比较法分析 CFGTL-界面对 EIS 测量数据的影响。结果表明，CFGTL-界面可以有效降低数据波动的变化和范围，这表明 CFGTL-界面可以减少“接触伪影”，提高检查的准确性。CFGTL-界面似乎是一种用于乳房 EIS 检查的有效电极-皮肤界面。
