Ahmed Shabina Ishtiaq, Jamil Sehrish, Ismatullah Humaira, Hussain Rashid, Bibi Shabana, Khandaker Mayeen Uddin, Naveed Aisha, Idris Abubakr M, Emran Talha Bin
Department of Plant Biotechnology, Atta-Ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), 44000, Islamabad, Pakistan.
The Standard College for Girls, 3/530 Paris Road, Sialkot Pakistan.
Saudi J Biol Sci. 2023 Mar;30(3):103561. doi: 10.1016/j.sjbs.2023.103561. Epub 2023 Jan 13.
COVID-19 is a pulmonary disease caused by SARS-CoV-2. More than 200 million individuals are infected by this globally. Pyrexia, coughing, shortness of breath, headaches, diarrhoea, sore throats, and body aches are among the typical symptoms of COVID-19. The virus enters into the host body by interacting with the ACE2 receptor. Despite many SARS-CoV-2 vaccines manufactured by distinct strategies but any evidence-based particular medication to combat COVID-19 is not available yet. However, further research is required to determine the safety and effectiveness profile of the present therapeutic approaches. In this study, we provide a summary of Traditional Arabic or Islamic medicinal (TAIM) plants' historical use and their present role as adjuvant therapy for COVID-19. Herein, six medicinal plants and have been studied based upon their pharmacological activities against viral infections. These plants include phytochemicals that have antiviral, immunomodulatory, antiasthmatic, antipyretic, and antitussive properties. These bioactive substances could be employed to control symptoms and enhance the development of a possible COVID-19 medicinal synthesis. To determine whether or if these TAIMs may be used as adjuvant therapy and are appropriate, a detailed evaluation is advised.
新冠肺炎是一种由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的肺部疾病。全球有超过2亿人感染了这种病毒。发热、咳嗽、呼吸急促、头痛、腹泻、喉咙痛和身体疼痛是新冠肺炎的典型症状。该病毒通过与血管紧张素转换酶2（ACE2）受体相互作用进入宿主身体。尽管通过不同策略生产了许多SARS-CoV-2疫苗，但目前尚无任何基于证据的对抗新冠肺炎的特效药物。然而，需要进一步研究以确定当前治疗方法的安全性和有效性。在本研究中，我们总结了传统阿拉伯或伊斯兰医学（TAIM）植物的历史用途及其作为新冠肺炎辅助治疗的当前作用。在此，基于六种药用植物对病毒感染的药理活性进行了研究。这些植物含有具有抗病毒、免疫调节、抗哮喘、解热和镇咳特性的植物化学物质。这些生物活性物质可用于控制症状并促进可能的新冠肺炎药物合成的发展。为了确定这些TAIMs是否可用作辅助治疗以及是否合适，建议进行详细评估。
