Sankoff David
Department of Mathematics, University of Ottawa, 585 King Edward Avenue, Ottawa K1N 6N5, Canada.
J Biol. 2009;8(7):66. doi: 10.1186/jbiol162. Epub 2009 Jul 24.
The 'action' in genome-level evolution lies not in the large gene-containing segments that are conserved among related species, but in the breakpoint regions between these segments. Two recent papers in BMC Genomics detail the pattern of repetitive elements associated with breakpoints and the epigenetic conditions under which breakage occurs.
基因组水平进化中的“作用”并不在于相关物种间保守的含大基因片段,而在于这些片段之间的断点区域。《BMC基因组学》最近发表的两篇论文详细阐述了与断点相关的重复元件模式以及发生断裂的表观遗传条件。