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国际血液采集和储存:血液制品的临床应用。

International blood collection and storage: clinical use of blood products.

机构信息

Joint Proteomics Laboratory, Ludwig Institute for Cancer Research & The Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville, Victoria, Australia.

出版信息

J Proteomics. 2010 Jan 3;73(3):386-95. doi: 10.1016/j.jprot.2009.07.011. Epub 2009 Aug 4.

DOI:10.1016/j.jprot.2009.07.011
PMID:19664733
Abstract

Human blood transfusion is the process of transferring blood or blood-based products from an individual into the circulatory system of another. From the theory of circulation of blood to the early practice of blood transfusion, transfusion medicine has been an important concept for many centuries. The practicality of transfusion, however, only became a possibility during and shortly after the Second World War. Today, blood and its derivatives play a critical role in worldwide health care systems, with blood components having direct clinical indications. Over the past several years worldwide organizations including the World Health Organization (WHO) have made a number of substantial improvements to the regulation of the worlds blood supply. This continuous supply plays a critical role throughout health care systems worldwide, with procedures for blood collection, processing, and storage now complex, standardised processes. As the areas of clinical validation of different disease states from blood-derived sources (i.e., disease biomarkers) move towards validation stages, the importance of controlled- and standardised-protocols is imperative.

摘要

人体输血是指将血液或基于血液的制品从一个人转移到另一个人的循环系统中的过程。从血液循环理论到早期的输血实践,输血医学已经是几个世纪以来的一个重要概念。然而,输血的实用性只是在第二次世界大战期间和之后才成为可能。如今,血液及其衍生物在全球卫生保健系统中发挥着至关重要的作用,血液成分具有直接的临床适应证。在过去几年中,包括世界卫生组织(WHO)在内的全球组织对世界血液供应的监管进行了多项重大改进。这种持续的供应在全球卫生保健系统中起着至关重要的作用,血液采集、处理和储存的程序现在已经是复杂的标准化流程。随着从血液来源(即疾病生物标志物)验证不同疾病状态的临床验证领域进入验证阶段,控制和标准化协议的重要性变得至关重要。

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