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尿道成形术后狭窄复发:一项系统评价

Stricture recurrence after urethroplasty: a systematic review.

作者信息

Meeks Joshua J, Erickson Bradley A, Granieri Michael A, Gonzalez Chris M

机构信息

Department of Urology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA.

出版信息

J Urol. 2009 Oct;182(4):1266-70. doi: 10.1016/j.juro.2009.06.027. Epub 2009 Aug 14.

Abstract

PURPOSE

Urethroplasty remains the gold standard for the management of urethral stricture disease with acceptable long-term success. However, the standard by which stricture recurrence is defined and evaluated after urethral reconstruction remains widely variable. We conducted a systematic review of the urological literature to determine how stricture recurrence is defined and evaluated.

MATERIALS AND METHODS

A systematic review was conducted on all contemporary urethroplasty articles published between 2000 and 2008. Using the term "urethroplasty" 302 articles were identified and evaluated. A total of 86 articles were included in the analysis.

RESULTS

The overall recurrence rate for all reconstructive procedures was 15.6%, which remained stable between 2000 and 2008. Stricture recurrence was determined by a mean of 3 (range 1 to 8) different diagnostic tests. The most common primary diagnostic tests for recurrence were uroflowmetry (56% of articles) and retrograde urethrography (51%). Cystourethroscopy was used as a primary screen to identify stricture recurrence in 25% of articles, and as a secondary procedure in another 21%. Recurrence was defined as the need for an additional surgical procedure or dilation in 75% and 52% of articles, respectively.

CONCLUSIONS

The methods used to determine stricture recurrence after urethroplasty remain widely variable. The use of a standardized surveillance protocol to define stricture recurrence after urethral reconstruction may allow more effective comparison of urethroplasty outcomes across institutions.

摘要

目的

尿道成形术仍是治疗尿道狭窄疾病的金标准,长期成功率令人满意。然而,尿道重建术后狭窄复发的定义和评估标准仍存在很大差异。我们对泌尿外科文献进行了系统回顾,以确定狭窄复发是如何定义和评估的。

材料与方法

对2000年至2008年间发表的所有当代尿道成形术文章进行系统回顾。使用“尿道成形术”一词,共识别并评估了302篇文章。共有86篇文章纳入分析。

结果

所有重建手术的总体复发率为15.6%,在2000年至2008年间保持稳定。狭窄复发平均通过3种(范围1至8种)不同的诊断测试来确定。复发最常见的主要诊断测试是尿流率测定(56%的文章)和逆行尿道造影(51%)。膀胱尿道镜检查在25%的文章中用作识别狭窄复发的主要筛查方法,在另外21%的文章中用作次要检查方法。分别在75%和52%的文章中,复发被定义为需要再次进行手术或扩张。

结论

尿道成形术后确定狭窄复发的方法仍存在很大差异。采用标准化的监测方案来定义尿道重建术后的狭窄复发,可能有助于更有效地比较不同机构的尿道成形术结果。

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