黎凡特地区Y染色体遗传景观的地理结构：沿海与内陆的对比
Geographical structure of the Y-chromosomal genetic landscape of the Levant: a coastal-inland contrast.
作者信息
El-Sibai Mirvat, Platt Daniel E, Haber Marc, Xue Yali, Youhanna Sonia C, Wells R Spencer, Izaabel Hassan, Sanyoura May F, Harmanani Haidar, Bonab Maziar Ashrafian, Behbehani Jaafar, Hashwa Fuad, Tyler-Smith Chris, Zalloua Pierre A
机构信息
The Lebanese American University, Chouran, Beirut 1102 2801, Lebanon.
出版信息
Ann Hum Genet. 2009 Nov;73(Pt 6):568-81. doi: 10.1111/j.1469-1809.2009.00538.x. Epub 2009 Aug 16.
Abstract
We have examined the male-specific phylogeography of the Levant and its surroundings by analyzing Y-chromosomal haplogroup distributions using 5874 samples (885 new) from 23 countries. The diversity within some of these haplogroups was also examined. The Levantine populations showed clustering in SNP and STR analyses when considered against a broad Middle-East and North African background. However, we also found a coastal-inland, east-west pattern of diversity and frequency distribution in several haplogroups within the small region of the Levant. Since estimates of effective population size are similar in the two regions, this strong pattern is likely to have arisen mainly from differential migrations, with different lineages introduced from the east and west.
摘要
我们通过分析来自23个国家的5874个样本（885个为新样本）的Y染色体单倍群分布，研究了黎凡特及其周边地区男性特有的系统地理学。我们还检测了其中一些单倍群内的多样性。当置于广阔的中东和北非背景下考虑时，黎凡特人群在单核苷酸多态性（SNP）和短串联重复序列（STR）分析中呈现出聚类现象。然而，我们也在黎凡特这个小区域内的几个单倍群中发现了多样性和频率分布的沿海-内陆、东西向模式。由于这两个区域的有效种群大小估计相似，这种强烈的模式很可能主要源于不同的迁移，即从东部和西部引入了不同的谱系。
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