Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, India.
Fitoterapia. 2010 Apr;81(3):162-6. doi: 10.1016/j.fitote.2009.08.014. Epub 2009 Aug 15.
Two new phenolic glycosides (1, 2), along with fourteen known compounds (3-16) have been isolated from the fruit of Cupressus sempervirens. The structures of these compounds were determined by spectroscopic analysis and were evaluated for their inhibitory activity against glycogen phosphorylase and glucose-6-phosphatase enzymes. Compounds 14 showed a moderate inhibition against glucose-6-phosphatase and 15 against glycogen phosphorylase enzymes.
从柏科植物柏木的果实中分离得到了两个新的酚糖苷(1、2)以及 14 个已知化合物(3-16)。通过光谱分析确定了这些化合物的结构,并评估了它们对糖原磷酸化酶和葡萄糖-6-磷酸酶的抑制活性。化合物 14 对葡萄糖-6-磷酸酶有中等抑制作用,化合物 15 对糖原磷酸化酶有抑制作用。