Harmanli Ozgur H, Okafor Obi, Ayaz Reyhan, Knee Alexander
From the Department of Obstetrics and Gynecology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts.
Obstet Gynecol. 2009 Sep;114(3):547-550. doi: 10.1097/AOG.0b013e3181b43808.
To compare the pain perception between lidocaine and plain aqueous gel during assessment of postvoid residual volume and the Q-tip test.
: Patients were randomly assigned to either to 2% lidocaine hydrochloride jelly or plain aqueous gel. The allocated gel was first used to lubricate a catheter that was inserted into the bladder to measure the postvoid residual volume. After removal of the catheter, a cotton swab, coated with the same allocated gel, was advanced to the urethrovesical junction until resistance was felt. The angle of the swab with the horizontal plane was measured at rest and with Valsalva maneuver. Relevant baseline characteristics and the Wong-Baker FACES pain scores (where 0 is for no pain and 5 for worst pain) were compared.
After randomization, lidocaine and the plain aqueous gel arms consisted of 69 and 68 women, respectively. Baseline characteristics of the groups were similar. Significantly fewer women in the lidocaine group (62.3%) reported any pain than those allocated to plain aqueous gel (80.9%) (odds ratio 0.39, 95% confidence interval 0.18-0.85). The median pain score was significantly lower in the lidocaine group (1, range 0-5) compared with 2 (range 0-4), P<.001).
When compared with plain aqueous gel, 2% lidocaine jelly significantly reduces pain perception during evaluation of postvoid residual volume and the Q-tip test.
I.
比较在评估残余尿量和棉签试验过程中利多卡因与普通水性凝胶的疼痛感知情况。
患者被随机分配至2%盐酸利多卡因凝胶组或普通水性凝胶组。将分配好的凝胶首先用于润滑插入膀胱以测量残余尿量的导管。拔除导管后,用涂有相同分配凝胶的棉签推进至尿道膀胱交界处,直至感觉到阻力。在静息状态和瓦尔萨尔瓦动作时测量棉签与水平面的夹角。比较相关基线特征和面部表情疼痛评分(0表示无疼痛,5表示最严重疼痛)。
随机分组后,利多卡因组和普通水性凝胶组分别有69名和68名女性。两组的基线特征相似。利多卡因组报告有任何疼痛的女性(62.3%)明显少于普通水性凝胶组(80.9%)(比值比0.39,95%置信区间0.18 - 0.85)。利多卡因组的疼痛评分中位数(1,范围0 - 5)显著低于普通水性凝胶组的2(范围0 - 4),P <.001)。
与普通水性凝胶相比,2%利多卡因凝胶在评估残余尿量和棉签试验过程中能显著降低疼痛感知。
I级