Departamento de Anatomia Patológica, Hospital Universitário João de Barros Barreto, Instituto de Ciências Biológicas, Universidade Federal do Pará, Campus Universitário do Guamá, 66075-900 Belém, PA, Brasil. .
Mem Inst Oswaldo Cruz. 2009 Jul;104(4):665-7. doi: 10.1590/s0074-02762009000400024.
The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high and low-risk HPV types. In this study, only 3% of tumour samples showed HPV infection. Our findings support the conclusion that, despite the high incidence of HPV infection in the geographic regions studied, HPV was not associated with a higher risk of prostate cancer. To our knowledge, this is the first study evaluating the frequency of HPV detection in prostatic tissue of individuals from Brazil.
在巴西北部，我们评估了 65 例前列腺肿瘤样本和 6 例前列腺良性增生样本中是否存在人乳头瘤病毒（HPV）。我们使用了一种高度敏感的测试方法，即线性阵列 HPV 基因分型测试，来检测 37 种高危和低危 HPV 类型。在这项研究中，只有 3%的肿瘤样本显示 HPV 感染。我们的研究结果支持这样的结论，即尽管在研究的地理区域 HPV 感染的发生率很高，但 HPV 与前列腺癌的高风险无关。据我们所知，这是第一项评估巴西人前列腺组织中 HPV 检测频率的研究。
