咖啡因摄入与流产：一项前瞻性队列研究。
Caffeine consumption and miscarriage: a prospective cohort study.
机构信息
Epidemiology Branch, Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, Maryland 20852, USA.
出版信息
Fertil Steril. 2010 Jan;93(1):304-6. doi: 10.1016/j.fertnstert.2009.07.992. Epub 2009 Sep 3.
Abstract
Caffeine consumption has been equivocally associated with miscarriage, despite an absence of prospective longitudinal measurement of caffeine intake during sensitive windows of human development. In response to this critical data gap, we analyzed daily caffeine consumption while attempting pregnancy through 12 menstrual cycles at risk for pregnancy and found that caffeine consumption did not increase the risk or hazard of miscarriage, even after adjusting for relevant covariates.
摘要
尽管在人类发育的敏感窗口期间对咖啡因摄入量进行前瞻性纵向测量的情况并不明确，但咖啡因的摄入与流产仍存在关联。为了解决这一关键数据空白，我们通过 12 个可能怀孕的月经周期，对尝试怀孕期间的每日咖啡因摄入量进行了分析，结果发现，即使在调整了相关协变量后，咖啡因的摄入也不会增加流产的风险或危害。
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5
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