Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania 15216, USA.
J Pain Symptom Manage. 2009 Nov;38(5):738-46. doi: 10.1016/j.jpainsymman.2009.04.023. Epub 2009 Sep 12.
The purposes of this study were 1) to assess and describe the occurrence, frequency, severity, and distress of symptoms reported by Taiwanese pediatric cancer patients who were between 10 and 18 years of age, and 2) to use statistical analysis to determine whether the multiple dimensions (i.e., frequency, severity, or distress) of the Memorial Symptom Assessment Scale (MSAS) 10-18 alone can provide sufficient useful information for the assessment of symptoms that patients report as distressing. A total of 144 Taiwanese pediatric cancer patients and their mothers participated in this cross-sectional study. The frequency of symptoms for all patients ranged from 52% for "lack of energy" to 10% for "feeling nervous." The most common symptoms (occurrence >40%) were "lack of energy," "lack of appetite," "feeling drowsy," "sweating," "worrying," "nausea," "dry mouth," "pain," and "lack of concentration." Patients in the "on-treatment group" had more distressing symptoms than those in the "off-treatment group." The severity and distress subscales did provide the most information for symptom assessment and were the two best subscales to represent the impact of symptoms on quality of life, fatigue, and internalizing behaviors. The findings of this study suggest that revising the current format of the MSAS 10-18 into three separate instruments (one for each of the subscales) might provide more accurate data for assessments. Such a modification would change the scoring system and provide for more accurate data analysis.
1）评估和描述 10-18 岁台湾儿科癌症患者报告的症状的发生、频率、严重程度和困扰程度；2）使用统计分析来确定 Memorial Symptom Assessment Scale（MSAS）10-18 的多个维度（即频率、严重程度或困扰程度）是否可以为评估患者报告的困扰症状提供足够有用的信息。共有 144 名台湾儿科癌症患者及其母亲参与了这项横断面研究。所有患者的症状频率范围从“缺乏能量”的 52%到“感到紧张”的 10%。最常见的症状（发生率>40%）为“缺乏能量”、“缺乏食欲”、“昏昏欲睡”、“出汗”、“担忧”、“恶心”、“口干”、“疼痛”和“注意力不集中”。“治疗中组”的患者比“治疗后组”的患者有更多的困扰症状。严重程度和困扰分量表确实为症状评估提供了最多的信息，是代表症状对生活质量、疲劳和内化行为影响的两个最佳分量表。本研究的结果表明，将当前的 MSAS 10-18 格式修订为三个单独的工具（每个分量表一个），可能会为评估提供更准确的数据。这种修改将改变评分系统，并提供更准确的数据分析。
