J Pediatr Health Care. 2019 Jul-Aug;33(4):404-414. doi: 10.1016/j.pedhc.2018.11.007. Epub 2019 Mar 5.
Malignancy- and cancer-related treatments lead to multiple symptoms. Although treatments focus on cure, few research studies have examined the symptoms that accompany these aggressive and complicated treatments. The purpose of the study was to evaluate the symptoms experienced by children at home. Children (n = 25) and adolescents (n = 33) diagnosed with cancer completed the Memorial Symptoms Assessment Scale during the 5 days at home after discharge from the hospital. The most frequent physical symptoms were fatigue (52.1%), nausea (50.7%), lack of appetite (43.7%), and pain (42.3%). The most frequent psychological symptoms were difficulty sleeping (21.1%), worrying (18.3%), feeling sad (18.3%), and feeling nervous (16.9%). Significant differences were found in the overall physical and psychosocial symptoms and Global Distress Index in patients with and without pain, fatigue, and nausea. Results indicated that physical and psychosocial symptoms and Global Distress Index increased as severity of pain, nausea, and fatigue increased. Children and adolescents were experiencing many symptoms at home but were often not reporting them.
恶性肿瘤和癌症相关治疗会引发多种症状。尽管治疗侧重于治愈，但很少有研究关注伴随这些侵袭性和复杂治疗而来的症状。本研究的目的是评估儿童在家中所经历的症状。患有癌症的儿童（n=25）和青少年（n=33）在出院后在家中度过的 5 天内完成了纪念症状评估量表。最常见的身体症状是疲劳（52.1%）、恶心（50.7%）、食欲不振（43.7%）和疼痛（42.3%）。最常见的心理症状是睡眠困难（21.1%）、担忧（18.3%）、悲伤（18.3%）和紧张（16.9%）。有无疼痛、疲劳和恶心的患者在整体身体和心理社会症状以及全球困扰指数方面存在显著差异。结果表明，随着疼痛、恶心和疲劳的严重程度增加，身体和心理社会症状以及全球困扰指数也会增加。儿童和青少年在家中会经历许多症状，但往往不会报告这些症状。
