Microbiology Department, Hospital Clinic, IDIBAPS, University of Barcelona, Spain.
Microb Pathog. 2009 Dec;47(6):305-7. doi: 10.1016/j.micpath.2009.09.007. Epub 2009 Sep 13.
One hundred seventy human uropathogenic Escherichia coli (UPEC) clinical isolates were compared with 35 E. coli strains isolated from feces of a control group to determine the presence of the set1, sen and astA genes encoding the ShET-1, ShET-2, and EAST toxins, respectively. Overall, 27 (16%), 8 (8%) and 0 UPEC isolates presented the set1B, the astA, and the sen genes, respectively. This is the first time the set gene has been found in UPEC clinical isolates.
将 170 株人源泌尿道致病性大肠杆菌(UPEC)临床分离株与 35 株来自对照组粪便的大肠杆菌菌株进行比较,以确定分别编码 ShET-1、ShET-2 和 EAST 毒素的 set1、sen 和 astA 基因的存在情况。总的来说,27(16%)、8(8%)和 0 UPEC 分离株分别携带 set1B、astA 和 sen 基因。这是首次在 UPEC 临床分离株中发现 set 基因。