Duong Timothy Q, Muir Eric R
Research Imaging Center, Department of Ophthalmology, University of Texas Health Science Center, San Antonio, TX, USA.
Jpn J Ophthalmol. 2009 Jul;53(4):352-67. doi: 10.1007/s10384-009-0688-1. Epub 2009 Sep 8.
This paper reviews recent developments in high-resolution magnetic resonance imaging (MRI) and its application to image anatomy, physiology, and function in the retina of animals. It describes technical issues and solutions in performing retinal MRI, anatomical MRI, blood oxygenation level-dependent functional MRI (fMRI), and blood-flow MRI both of normal retinas and of retinal degeneration. MRI offers unique advantages over existing retinal imaging techniques, including the ability to image multiple layers without depth limitation and to provide multiple clinically relevant data in a single setting. Retinal MRI has the potential to complement existing retinal imaging techniques.
本文综述了高分辨率磁共振成像(MRI)的最新进展及其在动物视网膜解剖结构、生理学和功能成像中的应用。它描述了在对正常视网膜和视网膜变性进行视网膜MRI、解剖MRI、血氧水平依赖性功能MRI(fMRI)和血流MRI时的技术问题及解决方案。与现有的视网膜成像技术相比,MRI具有独特的优势,包括能够对多层进行成像而不受深度限制,以及能够在单一检查中提供多个临床相关数据。视网膜MRI有潜力补充现有的视网膜成像技术。