• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

视网膜的磁共振成像。

Magnetic resonance imaging of the retina.

作者信息

Duong Timothy Q, Muir Eric R

机构信息

Research Imaging Center, Department of Ophthalmology, University of Texas Health Science Center, San Antonio, TX, USA.

出版信息

Jpn J Ophthalmol. 2009 Jul;53(4):352-67. doi: 10.1007/s10384-009-0688-1. Epub 2009 Sep 8.

DOI:10.1007/s10384-009-0688-1
PMID:19763752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2901235/
Abstract

This paper reviews recent developments in high-resolution magnetic resonance imaging (MRI) and its application to image anatomy, physiology, and function in the retina of animals. It describes technical issues and solutions in performing retinal MRI, anatomical MRI, blood oxygenation level-dependent functional MRI (fMRI), and blood-flow MRI both of normal retinas and of retinal degeneration. MRI offers unique advantages over existing retinal imaging techniques, including the ability to image multiple layers without depth limitation and to provide multiple clinically relevant data in a single setting. Retinal MRI has the potential to complement existing retinal imaging techniques.

摘要

本文综述了高分辨率磁共振成像（MRI）的最新进展及其在动物视网膜解剖结构、生理学和功能成像中的应用。它描述了在对正常视网膜和视网膜变性进行视网膜MRI、解剖MRI、血氧水平依赖性功能MRI（fMRI）和血流MRI时的技术问题及解决方案。与现有的视网膜成像技术相比，MRI具有独特的优势，包括能够对多层进行成像而不受深度限制，以及能够在单一检查中提供多个临床相关数据。视网膜MRI有潜力补充现有的视网膜成像技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/10390539ebb5/nihms-214498-f0013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/e74fa48009f7/nihms-214498-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/c7bddc37093d/nihms-214498-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/71b70f54e2b0/nihms-214498-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/0d8ddf40ac50/nihms-214498-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/760ade0246eb/nihms-214498-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/a280c4f0ca9b/nihms-214498-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/e8f056f65e34/nihms-214498-f0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/6617084662c6/nihms-214498-f0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/0b7a08cc2738/nihms-214498-f0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/ee25e30b3b37/nihms-214498-f0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/196b8922b292/nihms-214498-f0011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/5e62c7827114/nihms-214498-f0012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/10390539ebb5/nihms-214498-f0013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/e74fa48009f7/nihms-214498-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/c7bddc37093d/nihms-214498-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/71b70f54e2b0/nihms-214498-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/0d8ddf40ac50/nihms-214498-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/760ade0246eb/nihms-214498-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/a280c4f0ca9b/nihms-214498-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/e8f056f65e34/nihms-214498-f0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/6617084662c6/nihms-214498-f0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/0b7a08cc2738/nihms-214498-f0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/ee25e30b3b37/nihms-214498-f0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/196b8922b292/nihms-214498-f0011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/5e62c7827114/nihms-214498-f0012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af1/2901235/10390539ebb5/nihms-214498-f0013.jpg

相似文献

1
Magnetic resonance imaging of the retina.视网膜的磁共振成像。
Jpn J Ophthalmol. 2009 Jul;53(4):352-67. doi: 10.1007/s10384-009-0688-1. Epub 2009 Sep 8.
2
Layer-specific anatomical, physiological and functional MRI of the retina.视网膜的层特异性解剖、生理和功能磁共振成像。
NMR Biomed. 2008 Nov;21(9):978-96. doi: 10.1002/nbm.1311.
3
Anatomical, blood oxygenation level-dependent, and blood flow MRI of nonhuman primate (baboon) retina.非人类灵长类（狒狒）视网膜的解剖学、血氧水平依赖和血流 MRI
Magn Reson Med. 2011 Aug;66(2):546-54. doi: 10.1002/mrm.22853. Epub 2011 Feb 28.
4
MRI reveals differential regulation of retinal and choroidal blood volumes in rat retina.MRI 揭示了大鼠视网膜中视网膜和脉络膜血液体积的差异调节。
Neuroimage. 2011 Jan 15;54(2):1063-9. doi: 10.1016/j.neuroimage.2010.09.020. Epub 2010 Sep 17.
5
Functional imaging using the retinal function imager: direct imaging of blood velocity, achieving fluorescein angiography-like images without any contrast agent, qualitative oximetry, and functional metabolic signals.使用视网膜功能成像仪的功能成像：直接成像血流速度，无需任何造影剂即可获得类似荧光素血管造影的图像、定性血氧测定以及功能代谢信号。
Jpn J Ophthalmol. 2009 Jul;53(4):345-51. doi: 10.1007/s10384-009-0689-0. Epub 2009 Sep 8.
6
Blood-flow magnetic resonance imaging of the retina.视网膜血流磁共振成像
Neuroimage. 2008 Feb 15;39(4):1744-51. doi: 10.1016/j.neuroimage.2007.10.030. Epub 2007 Nov 1.
7
Magnetic resonance imaging of vascular oxygenation changes during hyperoxia and carbogen challenges in the human retina.磁共振成像在人类视网膜中观察高氧和碳氧合作用挑战期间血管氧合变化。
Invest Ophthalmol Vis Sci. 2011 Jan 5;52(1):286-91. doi: 10.1167/iovs.10-6108. Print 2011 Jan.
8
Lamina-specific functional MRI of retinal and choroidal responses to visual stimuli.基于视功能磁共振成像的视网膜和脉络膜对视觉刺激的反应特征。
Invest Ophthalmol Vis Sci. 2011 Jul 15;52(8):5303-10. doi: 10.1167/iovs.10-6438.
9
Blood flow magnetic resonance imaging of retinal degeneration.视网膜变性的血流磁共振成像
Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1824-30. doi: 10.1167/iovs.08-2188. Epub 2008 Oct 24.
10
Magnetic resonance imaging of the retina: from mice to men.视网膜的磁共振成像：从小鼠到人类。
Magn Reson Med. 2014 Apr;71(4):1526-30. doi: 10.1002/mrm.24797. Epub 2013 May 28.

引用本文的文献

1
Imaging the eye as a window to brain health: frontier approaches and future directions.将眼睛视为大脑健康之窗：前沿方法和未来方向。
J Neuroinflammation. 2024 Nov 29;21(1):309. doi: 10.1186/s12974-024-03304-3.
2
Application of Arterial Spin Labelling in the Assessment of Ocular Tissues.动脉自旋标记技术在眼部组织评估中的应用。
Biomed Res Int. 2016;2016:6240504. doi: 10.1155/2016/6240504. Epub 2016 Mar 15.
3
Choroidal blood flow decreases with age: an MRI study.脉络膜血流随年龄增长而减少：一项MRI研究。
Curr Eye Res. 2014 Oct;39(10):1059-67. doi: 10.3109/02713683.2014.892997. Epub 2014 Mar 21.
4
Postocclusive reactive hyperemia occurs in the rat retinal circulation but not in the choroid.闭塞后反应性充血发生在大鼠视网膜循环中，但不在脉络膜中。
Invest Ophthalmol Vis Sci. 2013 Jul 30;54(7):5123-31. doi: 10.1167/iovs.13-12404.
5
Magnetic resonance imaging of the retina: from mice to men.视网膜的磁共振成像：从小鼠到人类。
Magn Reson Med. 2014 Apr;71(4):1526-30. doi: 10.1002/mrm.24797. Epub 2013 May 28.
6
Decreased retinal-choroidal blood flow in retinitis pigmentosa as measured by MRI.通过磁共振成像测量发现色素性视网膜炎患者视网膜 - 脉络膜血流减少。
Doc Ophthalmol. 2013 Jun;126(3):187-97. doi: 10.1007/s10633-013-9374-1. Epub 2013 Feb 14.
7
Ultra high-resolution fMRI and electrophysiology of the rat primary somatosensory cortex.大鼠初级体感皮层的超高分辨率 fMRI 和电生理学研究。
Neuroimage. 2013 Jun;73:113-20. doi: 10.1016/j.neuroimage.2013.01.062. Epub 2013 Feb 4.
8
Review: magnetic resonance imaging techniques in ophthalmology.综述：眼科中的磁共振成像技术
Mol Vis. 2012;18:2538-60. Epub 2012 Oct 12.
9
MR imaging of papilledema and visual pathways: effects of increased intracranial pressure and pathophysiologic mechanisms.视乳头水肿和视觉通路的磁共振成像：颅内压增高的影响和病理生理机制。
AJNR Am J Neuroradiol. 2013 May;34(5):919-24. doi: 10.3174/ajnr.A3022. Epub 2012 Mar 15.
10
Magnetic resonance imaging indicates decreased choroidal and retinal blood flow in the DBA/2J mouse model of glaucoma.磁共振成像显示 DBA/2J 青光眼小鼠模型脉络膜和视网膜血流减少。
Invest Ophthalmol Vis Sci. 2012 Feb 1;53(2):560-4. doi: 10.1167/iovs.11-8429.

本文引用的文献

1
Adaptive-optics optical coherence tomography for high-resolution and high-speed 3D retinal in vivo imaging.用于高分辨率和高速三维视网膜活体成像的自适应光学光学相干断层扫描技术
Opt Express. 2005 Oct 17;13(21):8532-8546. doi: 10.1364/opex.13.008532.
2
Blood flow magnetic resonance imaging of retinal degeneration.视网膜变性的血流磁共振成像
Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1824-30. doi: 10.1167/iovs.08-2188. Epub 2008 Oct 24.
3
Layer-specific anatomical, physiological and functional MRI of the retina.视网膜的层特异性解剖、生理和功能磁共振成像。
NMR Biomed. 2008 Nov;21(9):978-96. doi: 10.1002/nbm.1311.
4
Temporal statistical analysis of laser speckle images and its application to retinal blood-flow imaging.激光散斑图像的时间统计分析及其在视网膜血流成像中的应用。
Opt Express. 2008 Jul 7;16(14):10214-9. doi: 10.1364/oe.16.010214.
5
Evaluating neural activity of retinal ganglion cells by flash-evoked intrinsic signal imaging in macaque retina.通过闪光诱发的内在信号成像评估猕猴视网膜中视网膜神经节细胞的神经活动。
Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4655-63. doi: 10.1167/iovs.08-1936. Epub 2008 Jun 6.
6
In vivo quantification of T1, T2, and apparent diffusion coefficient in the mouse retina at 11.74T.在11.74T磁场下对小鼠视网膜中的T1、T2和表观扩散系数进行活体定量分析。
Magn Reson Med. 2008 Apr;59(4):731-8. doi: 10.1002/mrm.21570.
7
Blood-flow magnetic resonance imaging of the retina.视网膜血流磁共振成像
Neuroimage. 2008 Feb 15;39(4):1744-51. doi: 10.1016/j.neuroimage.2007.10.030. Epub 2007 Nov 1.
8
Simplified laser-speckle-imaging analysis method and its application to retinal blood flow imaging.简化的激光散斑成像分析方法及其在视网膜血流成像中的应用。
Opt Lett. 2007 Aug 1;32(15):2188-90. doi: 10.1364/ol.32.002188.
9
Intrinsic signal imaging in macaque retina reveals different types of flash-induced light reflectance changes of different origins.猕猴视网膜的内在信号成像揭示了不同起源的不同类型的闪光诱导光反射变化。
Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2903-12. doi: 10.1167/iovs.06-1294.
10
Structural and functional MRI reveals multiple retinal layers.结构和功能磁共振成像显示出多个视网膜层。
Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17525-30. doi: 10.1073/pnas.0605790103. Epub 2006 Nov 6.