Duong Timothy Q
South Texas Veterans Health Care System, Research Imaging Institute, Department of Ophthalmology, University of Texas Health Science Center, San Antonio, Texas, USA.
Magn Reson Med. 2014 Apr;71(4):1526-30. doi: 10.1002/mrm.24797. Epub 2013 May 28.
This mini-review provides an overview of magnetic resonance imaging (MRI) applications to study rodent, cat, non-human primate, and human retinas. These techniques include T(1) - and T(2) -weighted anatomical, diffusion, blood flow, blood volume, blood-oxygenation level dependent, manganese-enhanced, physiological, and functional MRI. Applications to study the retinas in diabetic retinopathy, glaucoma, and retinal degeneration are also reviewed. MRI offers some unique advantages compared with existing imaging techniques and has the potential to further our understanding of physiology and function in healthy and diseased retinas.
本综述概述了磁共振成像(MRI)在研究啮齿动物、猫、非人灵长类动物和人类视网膜方面的应用。这些技术包括T(1)加权和T(2)加权解剖成像、扩散成像、血流成像、血容量成像、血氧水平依赖性功能磁共振成像、锰增强磁共振成像、生理磁共振成像和功能磁共振成像。还综述了MRI在糖尿病视网膜病变、青光眼和视网膜变性中视网膜研究的应用。与现有成像技术相比,MRI具有一些独特的优势,并且有潜力进一步加深我们对健康和患病视网膜的生理及功能的理解。