Department of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan.
Kaohsiung J Med Sci. 2009 Oct;25(10):530-6. doi: 10.1016/S1607-551X(09)70545-5.
This study investigated the relationship between Child Behavior Checklist (CBCL) symptoms and attention-deficit hyperactivity disorder (ADHD) subtypes [inattentive (ADHD-I) and combined (ADHD-C)] with or without comorbidities. Overall, 116 ADHD children were interviewed using the Mini-International Neuropsychiatric Interview to assess ADHD subtypes and comorbidities, and were then divided into four groups according to their subtypes and comorbidities. The CBCL was completed by the parents of the ADHD children. The association between behavioral symptom severity and groups was examined by comparing the CBCL scales of the four groups. The scores for the Aggressive Behavior (p = 0.014) and Anxiety/Depression scales (p = 0.033) were higher in patients with ADHD-I with comorbidities than with ADHD-I without comorbidities. In addition, the score for the Aggressive Behavior scale was higher in patients with ADHD-C without comorbidities than in patients with ADHD-I without comorbidities (p = 0.011). The scores for the six CBCL scales were all higher in patients with ADHD-C with comorbidities than in patients with ADHD-I without comorbidities. Our findings suggest a synergistic effect of the co-occurrence of comorbidities and the ADHD-C subtype on behavioral symptom severity. Physicians could use the CBCL scales to distinguish patients with more severe symptoms from patients with less severe symptoms.
本研究调查了儿童行为检查表（CBCL）症状与注意力缺陷多动障碍（ADHD）亚型（注意力不集中型[ADHD-I]和混合型[ADHD-C]）之间的关系，这些亚型伴有或不伴有共病。总体而言，116 名 ADHD 儿童接受了 Mini-国际神经精神访谈，以评估 ADHD 亚型和共病，然后根据他们的亚型和共病分为四组。ADHD 儿童的父母完成了 CBCL。通过比较四组的 CBCL 量表，检查了行为症状严重程度与组之间的关联。伴有共病的 ADHD-I 患者的攻击性行为（p=0.014）和焦虑/抑郁量表评分（p=0.033）高于无共病的 ADHD-I 患者。此外，无共病的 ADHD-C 患者的攻击性行为量表评分高于无共病的 ADHD-I 患者（p=0.011）。伴有共病的 ADHD-C 患者的 CBCL 的六个量表评分均高于无共病的 ADHD-I 患者。我们的研究结果表明，共病的发生和 ADHD-C 亚型的同时存在对行为症状的严重程度有协同作用。医生可以使用 CBCL 量表来区分症状更严重的患者和症状较轻的患者。
