眼表鳞状上皮肿瘤的局部化疗：现状。
Topical chemotherapy for ocular surface squamous neoplasia: current status.
机构信息
Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
出版信息
Br J Ophthalmol. 2010 May;94(5):532-5. doi: 10.1136/bjo.2009.160820. Epub 2009 Sep 23.
PMID:19776089
Abstract
Although there are no randomised trials directly comparing topical chemotherapeutic agents mitomycin-C, 5-fluorouracil, and interferon-alpha2b, published studies indicate equal efficacy of these agents for treatment of non-invasive ocular surface squamous neoplasia (80%-88%). 5-Fluorouracil may be preferred, given low incidence of serious side effects and low cost to the patient.
摘要
虽然没有直接比较局部化疗药物丝裂霉素 C、5-氟尿嘧啶和干扰素-α2b 的随机试验，但已发表的研究表明，这些药物治疗非侵袭性眼表鳞状上皮肿瘤的疗效相当（80%-88%）。5-氟尿嘧啶可能更受青睐，因为其严重副作用发生率低且对患者成本低。
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