Aslam Tariq, Chua Paul, Richardson Matthew, Patel Praveen, Musadiq Mohammed
Moorfields Eye Hospital, London, UK.
BMC Res Notes. 2009 Sep 28;2:196. doi: 10.1186/1756-0500-2-196.
Our aim was to develop an objective computerised system for measuring different types of retinal haemorrhages in differing digital images, for use as a research tool. Despite developing various fully automated systems of retinal haemorrhage measurement we ultimately found user interaction to be necessary to achieve satisfactory validity of segmentation, and developed an interactive system of haemorrhage assessment based on this.
The Haemorrhage Assessment System (HAS) presented here is an open access interactive program with graphical user interface allowing the ophthalmically trained user to easily delineate different haemorrhage types, optic disc and fovea. The system then automatically calculates a variety of measures, including mean haemorrhage area, total haemorrhage area, centre of mass, distance of centre of mass from disc and fovea, eccentricity and orientation. This paper presents evidence for the validity of HAS by comparison against established software and known results for geometric images.
The system should be of use to experimenters studying the distribution and topography of vitreoretinal haemorrhages who require a means of accurately quantifying an ophthalmologist's gold standard assessment of a digital image.
我们的目标是开发一种客观的计算机系统，用于测量不同数字图像中不同类型的视网膜出血，作为一种研究工具。尽管我们开发了各种全自动视网膜出血测量系统，但最终发现需要用户交互才能实现令人满意的分割有效性，并在此基础上开发了一种交互式出血评估系统。
本文介绍的出血评估系统（HAS）是一个具有图形用户界面的开放获取交互式程序，使经过眼科培训的用户能够轻松描绘不同的出血类型、视盘和黄斑。然后，该系统会自动计算各种测量值，包括平均出血面积、总出血面积、质心、质心与视盘和黄斑的距离、偏心率和方向。本文通过与既定软件和几何图像的已知结果进行比较，为HAS的有效性提供了证据。
该系统对于研究玻璃体视网膜出血分布和地形学的实验者应该是有用的，他们需要一种方法来准确量化眼科医生对数字图像的金标准评估。
