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2009 年中国 3 例甲型 H1N1 流感大流行早期感染病例的临床和流行病学特征。

Clinical and epidemiologic characteristics of 3 early cases of influenza A pandemic (H1N1) 2009 virus infection, People's Republic of China, 2009.

机构信息

Capital Medical University, Beijing, People's Republic of China.

出版信息

Emerg Infect Dis. 2009 Sep;15(9):1418-22. doi: 10.3201/eid1509.090794.

DOI:10.3201/eid1509.090794
PMID:19788809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2819857/
Abstract

On May 7, 2009, a national network was organized in the People's Republic of China for the surveillance, reporting, diagnosis, and treatment of influenza A pandemic (H1N1) 2009 virus infection (pandemic [H1N1] 2009). Persons with suspected cases are required to report to the Chinese Center for Disease Control and Prevention and the Ministry of Health within 24 hours; the patient's close contacts are then traced and placed in quarantine for 7 days. We report 3 confirmed early cases of pandemic (H1N1) 2009. Two cases were imported from United States; the other was imported from Canada. The patients exhibited fever and signs and other symptoms that were indistinguishable from those of seasonal influenza. Serial virologic monitoring of pharyngeal swabs showed that they were negative for pandemic (H1N1) 2009 virus by real-time reverse transcription-PCR 4-6 days after onset of illness. One close contact whose sample tested positive for pandemic (H1N1) 2009 virus had no symptoms during quarantine. A national network is essential for controlling pandemic (H1N1) 2009.

摘要

2009 年 5 月 7 日,中国组建了全国性网络,用于对甲型流感大流行(H1N1)2009 病毒感染的监测、报告、诊断和治疗(大流行[H1N1]2009)。要求疑似病例在 24 小时内报告中国疾病预防控制中心和卫生部;然后追踪患者的密切接触者并将其隔离 7 天。我们报告了 3 例确诊的大流行(H1N1)2009 早期病例。其中 2 例从美国输入,另 1 例从加拿大输入。这些患者表现出发热和其他与季节性流感无法区分的症状和体征。对咽拭子的连续病毒学监测显示,发病后 4-6 天实时逆转录-PCR 检测结果均为大流行(H1N1)2009 病毒阴性。1 例密切接触者在隔离期间样本检测出大流行(H1N1)2009 病毒阳性,但无任何症状。建立全国性网络对于控制大流行(H1N1)2009 至关重要。

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