Ishimi Yoshiko
National Institute of Health and Nutrition.
Clin Calcium. 2009 Oct;19(10):1506-13.
Soybean isoflavones are structurally similar to estrogen, and exhibit weak estrogenic activity. Although, a number of observational studies confirm the findings from the animal studies, the results from intervention studies are still controversial. One of the potential reasons for these inconsistencies could be considered individual differences in the isoflavone metabolism. In this report, the current topics of research on isoflavones and their relationship to bone health will be introduced.