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本文引用的文献

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A three-dimensional multispectral fluorescence optical tomography imaging system for small animals based on a conical mirror design.一种基于锥面镜设计的用于小动物的三维多光谱荧光光学断层成像系统。
Opt Express. 2009 Apr 27;17(9):7571-85. doi: 10.1364/oe.17.007571.
2
A higher order diffusion model for three-dimensional photon migration and image reconstruction in optical tomography.用于光学层析成像中三维光子迁移和图像重建的高阶扩散模型。
Phys Med Biol. 2009 Jan 7;54(1):65-88. doi: 10.1088/0031-9155/54/1/005. Epub 2008 Dec 5.
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Fast iterative image reconstruction methods for fully 3D multispectral bioluminescence tomography.用于全三维多光谱生物发光断层成像的快速迭代图像重建方法
Phys Med Biol. 2008 Jul 21;53(14):3921-42. doi: 10.1088/0031-9155/53/14/013. Epub 2008 Jun 30.
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A prototype PET scanner with DOI-encoding detectors.一种带有深度编码探测器的正电子发射断层扫描（PET）扫描仪原型。
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Multimodality molecular imaging with combined optical and SPECT/PET modalities.结合光学和单光子发射计算机断层扫描/正电子发射断层扫描（SPECT/PET）模式的多模态分子成像。
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Agonist-antagonist dilemma in molecular imaging: evaluation of a monomolecular multimodal imaging agent for the somatostatin receptor.分子成像中的激动剂-拮抗剂困境：一种用于生长抑素受体的单分子多模态成像剂的评估
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Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging.用于小动物成像的高光谱和多光谱生物发光光学断层扫描
Phys Med Biol. 2005 Dec 7;50(23):5421-41. doi: 10.1088/0031-9155/50/23/001. Epub 2005 Nov 8.
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Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging.用于体内小动物成像的微型PET II扫描仪的优化与性能评估。
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使用正电子发射断层扫描先验进行小动物成像的三维荧光光学层析成像。

Three-dimensional fluorescence optical tomography in small-animal imaging using simultaneous positron-emission-tomography priors.

机构信息

Department of Biomedical Engineering, University of California, Davis, Davis, California 95616, USA.

出版信息

Opt Lett. 2009 Oct 1;34(19):2933-5. doi: 10.1364/OL.34.002933.

DOI:10.1364/OL.34.002933
PMID:19794772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2856619/
Abstract

We propose three-dimensional fluorescence optical tomography imaging for small animals guided by simultaneous priors from positron emission tomography (PET). Using a sparsity regularization, the target prior from PET images was incorporated into the reconstruction algorithm for optical imaging. The method and algorithms are validated with numerical simulations and a phantom experiment performed on a combined optical-PET scanner based on a conical mirror geometry.

摘要

我们提出了一种基于正电子发射断层扫描 (PET) 同时先验信息引导的小动物三维荧光光学断层成像方法。利用稀疏正则化，将 PET 图像的目标先验信息纳入光学成像的重建算法中。该方法和算法通过数值模拟和基于锥形镜几何结构的光学-PET 扫描仪上的 phantom 实验进行了验证。