毛萼晶V碳骨架的合成
A synthesis of the carbon skeleton of maoecrystal V.
作者信息
Krawczuk Paul J, Schöne Niklas, Baran Phil S
机构信息
Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
出版信息
Org Lett. 2009 Nov 5;11(21):4774-6. doi: 10.1021/ol901963v.
Abstract
An enantioselective synthesis of the maoecrystal V (1) carbon skeleton is described. The key transformations include arylation of a 1,3-dicarbonyl compound with a triarylbismuth(V) dichloride species, oxidative dearomatization of a phenol, and a subsequent intramolecular Diels-Alder reaction.
摘要
描述了毛萼晶V（1）碳骨架的对映选择性合成。关键转化包括用三芳基铋（V）二氯化物对1,3 - 二羰基化合物进行芳基化、酚的氧化脱芳构化以及随后的分子内狄尔斯 - 阿尔德反应。
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