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栀子果实(Gardenia jasminoides Ellis)不同品种和成熟阶段的藏红花酸和京尼平苷含量及自由基清除活性。

Crocin and geniposide profiles and radical scavenging activity of gardenia fruits (Gardenia jasminoides Ellis) from different cultivars and at the various stages of maturation.

机构信息

Department of Chemistry, Zunyi Medical College Zhuhai Campus, Zhuhai Guangdong 519041, PR China.

出版信息

Fitoterapia. 2010 Jun;81(4):269-73. doi: 10.1016/j.fitote.2009.09.011. Epub 2009 Oct 6.

Abstract

The major components of gardenia fruits are geniposide and water soluble pigment crocins. In this study, we investigate crocins and geniposide profiles of gardenia fruits from different cultivars and at the various stages of maturation. DPPH scavenging activity of gardenia fruits from different cultivars and at the various stages of fruit maturation was also assayed. Quantitative determination of crocins in the gardenia at the various stages of maturation revealed a significant increase when ripening. However, geniposide content was negatively correlated with ripening stages. A significant difference was observed when comparing crocin content of different gardenia from various cultivars and geniposide content also showed marked variety. Current study indicated no relationship between crocin and geniposide content in gardenia fruits at the various stages of maturation and DPPH radical scavenging activity. Data showed that, although crocins feature markedly less DPPH scavenging activity than gardenia ethanol extract, total crocin content of gardenias collected in various cultivars correlate, to a certain degree, with radical scavenging effects of the Chinese traditional medicine (r=0.75).

摘要

栀子果实的主要成分是京尼平苷和水溶性色素藏红花素。本研究调查了不同品种和不同成熟阶段栀子果实的藏红花素和京尼平苷谱。还测定了不同品种和不同成熟阶段栀子果实的 DPPH 清除活性。定量测定不同成熟阶段栀子果实中的藏红花素含量,发现成熟时显著增加。然而,京尼平苷含量与成熟阶段呈负相关。不同品种栀子果实中藏红花素含量和京尼平苷含量差异显著。本研究表明,不同成熟阶段栀子果实中藏红花素和京尼平苷含量与 DPPH 自由基清除活性之间无相关性。数据表明,尽管藏红花素的 DPPH 清除活性明显低于栀子乙醇提取物,但不同品种采集的栀子总藏红花素含量与中药的自由基清除作用呈一定程度的相关性(r=0.75)。

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