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[口蹄疫疫苗与布鲁氏菌病疫苗联合使用的初步研究]

[Preliminary study of the combination of anti-foot-and-mouth disease and anti-brucellosis vaccines].

作者信息

Mastan M B, Amighi M, Ardelan A, Bandpay M R, Ebadi A, Farsi J

出版信息

Dev Biol Stand. 1976;35:437-43.

PMID:198311
Abstract

The results obtained with Brucella B19 strain, used as adjuvant and stimulant in the preparation of hyperimmune anti-foot-and-mouth disease serums on guinea pigs, have led the authors to carry out a series of experiments with a combined anti-foot-and-mouth disease and anti-brucellosis vaccine (strain B 19 Buck and Cotton). The search for neutralizing antibodies for foot-and-mouth disease has been undertaken by different methods. In the search for antibrucellic antibodies reactions such as seroagglutination, fixation of the complement, etc. have been used. The results obtained with combined vaccine are identical with those obtained with each of the monovalent vaccines.

摘要

在豚鼠制备超免疫抗口蹄疫血清时用作佐剂和刺激剂的布鲁氏菌B19菌株所获得的结果,促使作者开展了一系列关于口蹄疫和布鲁氏菌病联合疫苗(B 19 Buck和Cotton菌株)的实验。已通过不同方法来寻找口蹄疫中和抗体。在寻找抗布鲁氏菌抗体时,使用了血清凝集、补体结合等反应。联合疫苗所获得的结果与每种单价疫苗所获得的结果相同。

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