Gardner Paul P
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK.
Brief Funct Genomic Proteomic. 2009 Nov;8(6):444-50. doi: 10.1093/bfgp/elp042.
In this review we discuss bioinformatic issues in non-coding RNA analysis, in particular the annotation of genome sequences using covariance models. Some recent innovations for improving the speed and accuracy of covariance models is discussed.
在本综述中,我们讨论了非编码RNA分析中的生物信息学问题,特别是使用协方差模型对基因组序列进行注释。我们还讨论了一些用于提高协方差模型速度和准确性的最新创新方法。