分子机器还是多形聚集体：重新审视信号复合物
Molecular machines or pleiomorphic ensembles: signaling complexes revisited.
作者信息
Mayer Bruce J, Blinov Michael L, Loew Leslie M
机构信息
Richard D Berlin Center for Cell Analysis and Modeling, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-3301, USA.
出版信息
J Biol. 2009 Oct 16;8(9):81. doi: 10.1186/jbiol185.
Abstract
Signaling complexes typically consist of highly dynamic molecular ensembles that are challenging to study and to describe accurately. Conventional mechanical descriptions misrepresent this reality and can be actively counterproductive by misdirecting us away from investigating critical issues.
摘要
信号复合体通常由高度动态的分子集合组成，这些集合难以研究和准确描述。传统的力学描述歪曲了这一现实，并且可能会误导我们远离关键问题的研究，从而产生适得其反的效果。
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