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膜受体去除实验证实了EB病毒受体与人B淋巴瘤细胞系表面补体受体之间的关联。

Membrane receptor stripping confirms the association between EBV receptors and complement receptors on the surface of human B lymphoma lines.

作者信息

Yefenof E, Klein G

出版信息

Int J Cancer. 1977 Sep 15;20(3):347-52. doi: 10.1002/ijc.2910200305.

DOI:10.1002/ijc.2910200305
PMID:198382
Abstract

Complement (C3) receptors, EBV receptors, Fc receptors, membrane IgM and beta2microglobulin (beta 2m) were individually stripped from the surface of human B lymphoma lines. The cells were subsequently tested for their ability to absorb infectious EB virus. Stripping of Fc receptors, IgM and beta2m did not reduce EBV absorption. Stripping of either EBV receptors or C3 receptors eliminated or drastically reduced EBV-absorptive capacity. The results confirm the distinctive association between EBV receptors and C3 receptors on human lymphoma cells.

摘要

补体（C3）受体、EB病毒受体、Fc受体、膜IgM和β2微球蛋白（β2m）被分别从人B淋巴瘤细胞系表面去除。随后检测这些细胞吸收传染性EB病毒的能力。去除Fc受体、IgM和β2m并不降低EB病毒的吸收。去除EB病毒受体或C3受体则消除或显著降低了EB病毒的吸收能力。结果证实了人淋巴瘤细胞上EB病毒受体与C3受体之间独特的关联。

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Int J Cancer. 1977 Sep 15;20(3):347-52. doi: 10.1002/ijc.2910200305.
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引用本文的文献

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Clin Exp Immunol. 1980 Jul;41(1):166-72.
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Clin Exp Immunol. 1983 Aug;53(2):257-71.
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Use of fluoresceinated Epstein-Barr virus to study Epstein-Barr virus-lymphoid cell interactions.使用荧光标记的爱泼斯坦-巴尔病毒研究爱泼斯坦-巴尔病毒与淋巴细胞的相互作用。
J Virol. 1982 Feb;41(2):649-56. doi: 10.1128/JVI.41.2.649-656.1982.
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Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.人类B淋巴细胞的爱泼斯坦-巴尔病毒受体是C3d受体CR2。
Proc Natl Acad Sci U S A. 1984 Jul;81(14):4510-4. doi: 10.1073/pnas.81.14.4510.
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Human monoclonal antibodies.人源单克隆抗体。
Mol Cell Biochem. 1984 Jun;62(2):109-20. doi: 10.1007/BF00223301.
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J Clin Immunol. 1986 Jan;6(1):65-73. doi: 10.1007/BF00915366.
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