科学、技术与创新：临床研究中的护理职责
Science, technology, and innovation: nursing responsibilities in clinical research.
作者信息
Grady Christine, Edgerly Maureen
机构信息
Department of Bioethics, National Institutes of Health Clinical Center, Building 10/1C118, Bethesda, MD 20892, USA.
出版信息
Nurs Clin North Am. 2009 Dec;44(4):471-81. doi: 10.1016/j.cnur.2009.07.011.
Abstract
Clinical research is a systematic investigation of human biology, health, or illness involving human beings. It builds on laboratory and animal studies and often involves clinical trials, which are specifically designed to test the safety and efficacy of interventions in humans. Nurses are critical to the conduct of ethical clinical research and face clinical, ethical, and regulatory challenges in research in many diverse roles. Understanding and addressing the ethical challenges that complicate clinical research is integral to upholding the moral commitment that nurses make to patients, including protecting their rights and ensuring their safety as patients and as research participants.
摘要
临床研究是对涉及人类的生物学、健康或疾病进行的系统调查。它建立在实验室和动物研究的基础之上，并且通常涉及临床试验，这些试验是专门设计用于测试人类干预措施的安全性和有效性的。护士对于开展符合伦理的临床研究至关重要，并且在许多不同角色的研究中面临临床、伦理和监管方面的挑战。理解并应对使临床研究复杂化的伦理挑战，对于维护护士对患者做出的道德承诺不可或缺，这包括保护患者权利以及确保他们作为患者和研究参与者的安全。
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本文引用的文献
1
The Belmont Report. Ethical principles and guidelines for the protection of human subjects of research.《贝尔蒙报告》。保护人类研究受试者的伦理原则与准则。
J Am Coll Dent. 2014 Summer;81(3):4-13.
2
Guidelines to support nurse-researchers reflect on role conflict in qualitative interviewing.支持护士研究者反思定性访谈中角色冲突的指南。
Open Nurs J. 2008;2:58-62. doi: 10.2174/1874434600802010058. Epub 2008 Jun 10.
3
Ethical components of researcher researched relationships in qualitative interviewing.定性访谈中研究者与被研究者关系的伦理组成部分。
Qual Health Res. 2007 Oct;17(8):1149-59. doi: 10.1177/1049732307308305.
4
The role and potential contribution of clinical research nurses to clinical trials.临床研究护士在临床试验中的作用及潜在贡献。
J Clin Nurs. 2008 Feb;17(4):549-57. doi: 10.1111/j.1365-2702.2006.01872.x. Epub 2007 Apr 5.
5
Nurses' attitudes toward nursing research at a metropolitan medical center.
Appl Nurs Res. 2007 Feb;20(1):24-31. doi: 10.1016/j.apnr.2005.11.003.
6
Addressing nurses' ethical concerns about research in critical care settings.解决护士对重症监护环境中研究的伦理担忧。
Nurs Adm Q. 2006 Jan-Mar;30(1):67-75. doi: 10.1097/00006216-200601000-00010.
7
Nurse researcher: always a researcher, sometimes a nurse.护士研究者：永远是研究者，有时是护士。
Collegian. 2001 Oct;8(4):33-9. doi: 10.1016/s1322-7696(08)60032-3.
8
Development of a measure to delineate the clinical trials nursing role.制定一项用于界定临床试验护理角色的措施。
Oncol Nurs Forum. 2004 May 12;31(3):E64-8. doi: 10.1188/04.ONF.E64-E68. Print 2004 May.
9
Clinician perspectives on participation in research.临床医生对参与研究的看法。
J Midwifery Womens Health. 2004 Jan-Feb;49(1):47-50. doi: 10.1016/j.jmwh.2003.09.013.
10
The invisible hand in clinical research: the study coordinator's critical role in human subjects protection.临床研究中的无形之手：研究协调员在保护人类受试者方面的关键作用。
J Law Med Ethics. 2002 Fall;30(3):411-9. doi: 10.1111/j.1748-720x.2002.tb00410.x.
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