Grady Christine, Edgerly Maureen
Department of Bioethics, National Institutes of Health Clinical Center, Building 10/1C118, Bethesda, MD 20892, USA.
Nurs Clin North Am. 2009 Dec;44(4):471-81. doi: 10.1016/j.cnur.2009.07.011.
Clinical research is a systematic investigation of human biology, health, or illness involving human beings. It builds on laboratory and animal studies and often involves clinical trials, which are specifically designed to test the safety and efficacy of interventions in humans. Nurses are critical to the conduct of ethical clinical research and face clinical, ethical, and regulatory challenges in research in many diverse roles. Understanding and addressing the ethical challenges that complicate clinical research is integral to upholding the moral commitment that nurses make to patients, including protecting their rights and ensuring their safety as patients and as research participants.
临床研究是对涉及人类的生物学、健康或疾病进行的系统调查。它建立在实验室和动物研究的基础之上，并且通常涉及临床试验，这些试验是专门设计用于测试人类干预措施的安全性和有效性的。护士对于开展符合伦理的临床研究至关重要，并且在许多不同角色的研究中面临临床、伦理和监管方面的挑战。理解并应对使临床研究复杂化的伦理挑战，对于维护护士对患者做出的道德承诺不可或缺，这包括保护患者权利以及确保他们作为患者和研究参与者的安全。
