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癌症相关性疲劳及其与抑郁和焦虑的关系:系统综述。

Cancer-related fatigue and its associations with depression and anxiety: a systematic review.

机构信息

Psychology Department, Indiana University Purdue University, Indianapolis, IN 46202, USA.

出版信息

Psychosomatics. 2009 Sep-Oct;50(5):440-7. doi: 10.1176/appi.psy.50.5.440.

Abstract

BACKGROUND

Fatigue is an important symptom in cancer and has been shown to be associated with psychological distress.

OBJECTIVE

This review assesses evidence regarding associations of cancer-related fatigue with depression and anxiety.

METHOD

Database searches yielded 59 studies reporting correlation coefficients or odds ratios.

RESULTS

The combined sample size was 12,103. Almost all studies showed a correlation of fatigue with depression and with anxiety. However, 31 different instruments were used to assess fatigue, suggesting a lack of consensus on measurement.

CONCLUSION

This review confirms the association of fatigue with depression and anxiety. Directionality needs to be better delineated in longitudinal studies.

摘要

背景

疲劳是癌症的一个重要症状,并且已经表明与心理困扰有关。

目的

本综述评估了癌症相关疲劳与抑郁和焦虑之间关联的证据。

方法

数据库检索产生了 59 项报告相关系数或优势比的研究。

结果

合并样本量为 12103。几乎所有研究都表明疲劳与抑郁和焦虑相关。然而,有 31 种不同的工具用于评估疲劳,这表明在测量方面缺乏共识。

结论

本综述证实了疲劳与抑郁和焦虑之间的关联。在纵向研究中需要更好地描述方向性。

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