Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA.
Arch Virol. 2009;154(12):1959-65. doi: 10.1007/s00705-009-0513-7. Epub 2009 Oct 25.
The family Partitiviridae includes plant and fungal viruses with bisegmented dsRNA genomes and isometric virions in which the two genome segments are packaged separately and used as templates for semiconservative transcription by the viral polymerase. A new genus, Cryspovirus, has been approved for this family. Its name is based on that of the host genus, Cryptosporidium, which encompasses several species of apicomplexan parasites that infect a wide range of mammals, birds, and reptiles, and are a major cause of human diarrheal illness worldwide. The type species of the new genus is Cryptosporidium parvum virus 1. Distinguishing characteristics include infection of a protozoan host, a smaller capsid protein than found in other members of the family Partitiviridae, and sequence-based phylogenetic divergence.
联体病毒科包含具有双节段 dsRNA 基因组和等轴对称病毒粒子的植物和真菌病毒，其中两个基因组节段分别包装，并用作病毒聚合酶进行半保守转录的模板。该科已批准设立一个新属，Cryspovirus。其名称基于宿主属 Cryptosporidium，Cryptosporidium 包含几种感染广泛的哺乳动物、鸟类和爬行动物的顶复门寄生虫，是全世界人类腹泻病的主要病因。新属的模式种是 Cryptosporidium parvum virus 1。其鉴别特征包括感染原生动物宿主、比联体病毒科其他成员小的衣壳蛋白以及基于序列的系统发育差异。
