Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands.
J Clin Epidemiol. 2010 Apr;63(4):384-8. doi: 10.1016/j.jclinepi.2009.07.009. Epub 2009 Oct 28.
Triage systems, developed by consensus of experts and based on decision rules, are typically not validated. The objective is to discuss the challenges to evaluate the reliability and validity of triage systems.
Theoretical-conceptual approach to validate triage systems.
The consensus-based triage systems have to be applied to a broad population with a variety of signs and symptoms. For the individual patient-specific decision, rules are used and the outcome measure is, typically, one of five prognosis-specific urgency categories. In contrast, prediction rules in diagnostic research are developed for a narrow specific subpopulation and based on a combination of parameters to predict presence of a specific diagnosis. Reliability is based on case scenario and simultaneous triage studies. The first step in triage validation is to decide on the best proxy for prognosis, "the reference standard" for the urgency classification. The next step is modification of the triage decision rules, including a multivariate approach. The final step is the validation in different settings and to evaluate the impact in clinical practice.
Triage should be viewed as diagnostic research and would benefit if it would use the available methodology in diagnostic research.
通过专家共识制定并基于决策规则的分诊系统通常未经验证。本研究旨在讨论评估分诊系统可靠性和有效性所面临的挑战。
分诊系统验证的理论概念方法。
基于共识的分诊系统必须应用于具有各种体征和症状的广泛人群。对于特定个体患者的决策,使用规则,并且结果测量通常是五个预后特定紧急类别之一。相比之下,诊断研究中的预测规则是为特定的狭窄亚人群开发的,并基于参数组合来预测特定诊断的存在。可靠性基于病例场景和同时的分诊研究。分诊验证的第一步是确定预后的最佳替代指标,即紧急分类的“参考标准”。下一步是修改分诊决策规则,包括采用多变量方法。最后一步是在不同环境中进行验证,并评估其对临床实践的影响。
分诊应被视为诊断研究,如果它能够利用诊断研究中现有的方法学,将会从中受益。