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锌和低渗口服补液盐治疗腹泻:再次呼吁采取行动。

Zinc and low osmolarity oral rehydration salts for diarrhoea: a renewed call to action.

机构信息

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

出版信息

Bull World Health Organ. 2009 Oct;87(10):780-6. doi: 10.2471/blt.08.058990.

DOI:10.2471/blt.08.058990
PMID:19876545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2755312/
Abstract

In 2004, WHO and the United Nations Children's Fund (UNICEF) released a joint statement recommending a new lower osmolarity oral rehydration salts (ORS) formulation and zinc supplementation for diarrhoea management. More than 5 years later, diarrhoea remains the second leading cause of death and few children in developing countries are receiving these life-saving interventions. Many countries are stalled in the technicalities of adapting national policy, while others struggle to find the funds for start-up activities. For nearly all countries, zinc supplements for children are not available locally; thus, zinc procurement continues to be a major obstacle. Global resources have not been sufficient to bring diarrhoea management to the forefront; thus, the introduction of these new recommendations has remained slow. Revitalizing diarrhoea management must become an international priority if we are going to reduce the burden of diarrhoea deaths and overall child mortality around the world.

摘要

2004 年,世界卫生组织(世卫组织)和联合国儿童基金会(儿童基金会)发布了一份联合声明,建议使用新的低渗透压口服补液盐(ORS)配方和补锌来治疗腹泻。5 年多以后,腹泻仍然是导致死亡的第二大原因,而发展中国家很少有儿童接受这些救命干预措施。许多国家在调整国家政策的细节方面陷入僵局,而另一些国家则在为启动活动寻找资金。对于几乎所有国家来说,儿童用锌补充剂都无法在当地获得;因此,锌的采购仍然是一个主要障碍。全球资源还不足以使腹泻管理成为优先事项;因此,这些新建议的推出仍然缓慢。如果我们要减轻腹泻死亡和全球儿童总体死亡率的负担,那么振兴腹泻管理就必须成为一项国际优先事项。

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本文引用的文献

1
Effect of HIV/AIDS and malaria on the context for introduction of zinc treatment and low-osmolarity ORS for childhood diarrhoea.艾滋病毒/艾滋病和疟疾对引入锌治疗及低渗口服补液盐治疗儿童腹泻背景的影响。
J Health Popul Nutr. 2008 Mar;26(1):1-11.
2
Multi-country analysis of the effects of diarrhoea on childhood stunting.腹泻对儿童发育迟缓影响的多国分析。
Int J Epidemiol. 2008 Aug;37(4):816-30. doi: 10.1093/ije/dyn099. Epub 2008 Jun 20.
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Effectiveness of zinc supplementation plus oral rehydration salts compared with oral rehydration salts alone as a treatment for acute diarrhea in a primary care setting: a cluster randomized trial.在基层医疗环境中,补锌加口服补液盐与单纯口服补液盐治疗急性腹泻的效果比较:一项整群随机试验。
Pediatrics. 2008 May;121(5):e1279-85. doi: 10.1542/peds.2007-1939.
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Countdown to 2015: assessment of donor assistance to maternal, newborn, and child health between 2003 and 2006.2015年倒计时:2003年至2006年期间对孕产妇、新生儿和儿童健康的捐助援助评估
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Countdown to 2015 for maternal, newborn, and child survival: the 2008 report on tracking coverage of interventions.2015年孕产妇、新生儿和儿童生存倒计时:2008年干预措施覆盖情况跟踪报告
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