Alabbadi Ibrahim, Crealey Grainne, Turner Kathryn, Rafferty Therese, Keenan Lynn, Murray Penny, McElnay James C
Biopharmaceutics and Clinical Pharmacy Department, Faculty of Pharmacy, University of Jordan, Amman, Jordan.
Pharm World Sci. 2010 Feb;32(1):43-51. doi: 10.1007/s11096-009-9339-3. Epub 2009 Oct 31.
The objective of this research was to examine differences in patterns of statin prescribing between Northern Ireland and England both before and after the introduction of the Quality and Outcomes Framework (QOF).
Primary care practices in Northern Ireland and England. Method Northern Ireland practices were matched with practices in England, statin prescribing data and QOF achievement scores (for the first year post-QOF) were obtained. Crude prescribing data from matched practices were manipulated to provide a data set of Defined Daily Doses (DDDs)/1,000 patients and cost/DDD/1,000 patients for each statin drug entity covering 1 year before and after the introduction of QOF. QOF achievements were converted into percentage scores for matched practices.
Cost per defined daily dose (DDD) per 1,000 patients.
Significantly less statins (DDD/1,000 patients) were dispensed in Northern Ireland compared with the matched region in England both before and after the introduction of QOF (P < 0.001). However, significantly more statins were dispensed in both regions after the introduction of QOF. As a result of the introduction of QOF, the cost/DDD/1,000 patients rose by pound13.17 in NI, but fell by pound3.76 in the matched region in England.
Strategies should be considered to educate prescribers on cost-effectiveness by increasing their awareness of the negative budgetary impact resulting from early adoption of new and expensive statins and by encouraging generic prescribing.
本研究的目的是调查在引入质量与结果框架(QOF)之前和之后,北爱尔兰和英格兰他汀类药物处方模式的差异。
北爱尔兰和英格兰的基层医疗实践。方法:将北爱尔兰的医疗机构与英格兰的医疗机构进行匹配,获取他汀类药物处方数据和QOF成就得分(QOF实施后的第一年)。对匹配医疗机构的原始处方数据进行处理,以提供每种他汀类药物实体在QOF引入前后1年的限定日剂量(DDD)/1000患者数据集和成本/DDD/1000患者数据集。将QOF成就转换为匹配医疗机构的百分比得分。
每1000患者的限定日剂量(DDD)成本。
在引入QOF之前和之后,北爱尔兰发放的他汀类药物(DDD/1000患者)均显著少于英格兰的匹配地区(P<0.001)。然而,在引入QOF之后,两个地区发放的他汀类药物均显著增多。由于引入了QOF,北爱尔兰每1000患者的成本/DDD增加了13.17英镑,而英格兰匹配地区则下降了3.76英镑。
应考虑采取策略,通过提高处方医生对早期采用新的昂贵他汀类药物所产生的负面预算影响的认识,并鼓励使用通用名药物处方,来对他们进行成本效益方面的教育。