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巩膜扣带术与原发性玻璃体切除术治疗孔源性视网膜脱离的研究(SPR 研究):再手术风险因素的多事件分析。SPR 研究报告第 4 号。

Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR study): multiple-event analysis of risk factors for reoperations. SPR Study report no. 4.

机构信息

Institut für Medizinische Statistik, Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany.

出版信息

Acta Ophthalmol. 2011 Nov;89(7):622-8. doi: 10.1111/j.1755-3768.2009.01766.x. Epub 2009 Nov 11.

Abstract

PURPOSE

To identify risk factors that may lead to reoperations following primary vitrectomy (PV) and scleral buckling surgery (SB) for rhegmatogenous retinal detachment (RRD).

METHODS

Analysis of the association between distinct parameters and the necessity for reoperations in the 'Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study' (SPR Study) using an Andersen-Gill-mean intensity model.

RESULTS

The risk for recurrent reoperations is significantly reduced by primary vitrectomy (PV) compared to scleral buckling (SB) in pseudophakic eyes (p = 0.0009) and increased after PV compared to SB in phakic eyes (p < 0.0001). Additional significant risk factors were in the pseudophakic group preoperative deterioration of visual acuity (p = 0.0226), YAG capsulotomy (p = 0.0043), large breaks (p = 0.0290), number of affected quadrants (p = 0.0387), retinal incarceration during surgery (p = 0.0115), number of breaks (p < 0.0001) and symptomatic visual field defect (p = 0.0463). In the phakic group, associated risk factors were low intraocular pressure (p = 0.0013) and persistent intraoperative detachment at the buckle (p = 0.0184).

CONCLUSION

Reoperations are used as an indicator for the quality and efficacy of surgical techniques. Using a refined multivariate survival model, distinct factors were identified and associated with one or more reoperations after PV or SB in RRD surgery. This information should be useful in the decision process regarding the surgical approach.

摘要

目的

确定导致原发性玻璃体切除术(PV)和巩膜扣带术(SB)治疗孔源性视网膜脱离(RRD)后再次手术的风险因素。

方法

使用 Andersen-Gill-平均强度模型分析“巩膜扣带术与孔源性视网膜脱离的原发性玻璃体切除术研究”(SPR 研究)中不同参数与再次手术必要性之间的关联。

结果

与 SB 相比,在无晶状体眼中,PV 显著降低了再次手术的风险(p = 0.0009),而在晶状体眼中,PV 后再次手术的风险增加(p < 0.0001)。在无晶状体眼中,另外两个显著的风险因素是术前视力下降(p = 0.0226)、YAG 后囊切开术(p = 0.0043)、大裂孔(p = 0.0290)、受累象限数(p = 0.0387)、术中视网膜嵌顿(p = 0.0115)、裂孔数量(p < 0.0001)和症状性视野缺损(p = 0.0463)。在晶状体眼中,相关风险因素是低眼压(p = 0.0013)和扣带术中持续脱离(p = 0.0184)。

结论

再次手术被用作手术技术质量和疗效的指标。使用改进的多变量生存模型,确定了不同的因素,并将其与 RRD 手术后 PV 或 SB 后的一次或多次手术相关联。这些信息对于手术方法的决策过程应该是有用的。

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