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巩膜扣带术与原发性玻璃体切除术治疗孔源性视网膜脱离的研究(SPR 研究):解剖学结果风险评估。SPR 研究报告第 7 号。

Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR study): Risk assessment of anatomical outcome. SPR study report no. 7.

机构信息

Department of Ophthalmology, Georg-August University Hospital, Goettingen, Germany.

出版信息

Acta Ophthalmol. 2013 May;91(3):282-7. doi: 10.1111/j.1755-3768.2011.02344.x. Epub 2012 Feb 15.

Abstract

PURPOSE

The 'Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study' (SPR study) is a randomized multicentre trial comparing primary vitrectomy (PV) and scleral buckling surgery (SB) for rhegmatogenous retinal detachment (RRD). This subanalysis was conducted to identify risk factors associated with anatomical outcomes.

METHODS

Relating the anatomical success results at the 1-year follow-up visit to pre- and intraoperative findings using multivariate statistical methods.

RESULTS

In the phakic subtrial, anatomical success was negatively associated with the number of breaks (p < 0.0001), break extension > 1 clock hour (p = 0.0005) and intraoperative use of cryotherapy (p = 0.0484). It was positively associated with retinal breaks with irregular edges (p = 0.0353) and subretinal fluid drainage (p = 0.0155). In the pseudophakic/aphakic subtrial, anatomical success was negatively associated with the number of retinal breaks (p = 0.0004) and previous YAG capsulotomy (p = 0.0256), and the combined effect of the surgical procedure and intraoperative use of laser (p = 0.0229).

CONCLUSION

Primary anatomical success is an important result for patients undergoing RRD surgery. Our data demonstrate that the final anatomical outcome is related to a higher preoperative number of breaks and cryotherapy in phakic eyes. Additional risk factors varied between phakic and pseudophakic subgroups. Our findings may be used to facilitate the prognosis of future patients with RRD.

摘要

目的

“孔源性视网膜脱离巩膜扣带术与玻璃体切除术的比较研究”(SPR 研究)是一项随机多中心试验,比较了孔源性视网膜脱离(RRD)的玻璃体切除术(PV)和巩膜扣带术(SB)。本亚分析旨在确定与解剖学结果相关的危险因素。

方法

使用多变量统计方法将 1 年随访时的解剖学成功结果与术前和术中发现相关联。

结果

在有晶状体亚组中,解剖学成功与裂孔数量(p<0.0001)、裂孔延伸>1 个时钟小时(p=0.0005)和术中使用冷冻疗法(p=0.0484)呈负相关。它与视网膜裂孔边缘不规则(p=0.0353)和视网膜下液引流(p=0.0155)呈正相关。在无晶状体/晶状体切除亚组中,解剖学成功与视网膜裂孔数量(p=0.0004)和先前的 YAG 后囊切开术(p=0.0256)呈负相关,手术程序和术中使用激光的联合效应(p=0.0229)也是如此。

结论

原发性解剖学成功是接受 RRD 手术的患者的一个重要结果。我们的数据表明,最终的解剖学结果与术前裂孔数量较多和有晶状体眼冷冻疗法有关。在有晶状体和无晶状体亚组之间,额外的危险因素有所不同。我们的研究结果可用于帮助预测未来的 RRD 患者的预后。

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