海洋螺旋藻对四氧嘧啶诱导糖尿病大鼠胰岛β细胞的影响。
Alterations in beta-islets of Langerhans in alloxan-induced diabetic rats by marine Spirulina platensis.
机构信息
Department of Biochemistry & Molecular Biology, Pondicherry University, Kalapet, Puducherry, India.
出版信息
J Enzyme Inhib Med Chem. 2009 Dec;24(6):1253-6. doi: 10.3109/14756360902827240.
Marine Spirulina platensis may potentially influence the metabolic process in animal cells, and the effect of marine Spirulina platensis in normal and alloxan-induced diabetic rats was therefore investigated. Normal and diabetic rats (albino Wistar strain) were orally administered marine Spirulina platensis for 30 days and their blood levels of glucose and insulin and body weight changes were determined. Pancreatic histopathology was also noted. Treatment with marine Spirulina platensis caused significant alterations in the content of these indicators and therefore in the antidiabetic capacity of the treated animals compared to control rats.
海洋螺旋藻可能会影响动物细胞的新陈代谢过程，因此研究了海洋螺旋藻对正常和四氧嘧啶诱导的糖尿病大鼠的影响。正常和糖尿病大鼠（白化 Wistar 品系）经口给予海洋螺旋藻 30 天，并测定其血糖和胰岛素水平以及体重变化。还观察了胰腺组织病理学变化。与对照组大鼠相比，海洋螺旋藻治疗导致这些指标含量发生显著变化，从而使治疗动物的抗糖尿病能力发生变化。
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