Crabb C V
Arch Ophthalmol. 1977 Oct;95(10):1866-70. doi: 10.1001/archopht.1977.04450100168024.
Subconjunctival dibutyryl 3',5' cyclic adenosine monophosphoric acid (DBcAMP) produced a statistically significant reduction of ulceration in the alkaliburned rabbit cornea. No effect on epithelial cell growth was observed. DBcAMP also caused a statistically significant acceleration of corneal neovascularization in the first two weeks postburn. Medroxyprogesterone acetate also affected the development of corneal ulcers postalkali burn, but in a less well-defined manner. Dinoprost and indomethacin did not seem to influence this lesion. Cyclic adenosine monophosphoric acid may therefore possess a potential for use in the alkali-burned human eye.
结膜下注射二丁酰3',5'-环磷酸腺苷（DBcAMP）可使碱烧伤兔角膜的溃疡形成有统计学意义的显著减少。未观察到对上皮细胞生长有影响。DBcAMP还使烧伤后前两周角膜新生血管形成有统计学意义的显著加速。醋酸甲羟孕酮也影响碱烧伤后角膜溃疡的发展，但方式不太明确。地诺前列素和吲哚美辛似乎不影响这种损伤。因此，环磷酸腺苷可能具有用于碱烧伤人眼的潜力。
