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评估尼日利亚拉各斯部分孕妇的血液和尿液中的铅含量。

Assessment of blood and urine lead levels of some pregnant women residing in Lagos, Nigeria.

机构信息

Department of Environmental Management and Toxicology, University of Agriculture, P.M. B 2240, Abeokuta, Nigeria.

出版信息

Environ Monit Assess. 2010 Nov;170(1-4):467-74. doi: 10.1007/s10661-009-1247-4. Epub 2009 Nov 14.

DOI:10.1007/s10661-009-1247-4
PMID:19915952
Abstract

Assessment of lead in blood (BLL) and lead in urine (ULL) of some non-occupationally exposed, nonsmoking 214 pregnant Nigerian women, aged 17 to 49 years, and resident in Lagos was carried out using atomic absorption spectrometry with control subjects consisting of 113 nonpregnant women. From results, the mean BLL and ULL (μg/dL) for pregnant women (59.5±2.1; 29.4±1.1) were significantly (p<0.01) higher than the values obtained for nonpregnant women (27.7±1.1; 9.2±0.6). BLL found in women in the first, second, and third trimesters were 57.2±2.3, 61.6±2.2, and 63.1±1.8, respectively. ULL could not serve to predict BLL due to weak correlations (r=-0.06 to +0.15; p>0.10). Study is a contribution to blood and urine lead status of Nigerian pregnant women, being relevant for healthcare management purposes, public health decision making, and possible primary prevention activities.

摘要

对 214 名年龄在 17 至 49 岁、非职业暴露且不吸烟的尼日利亚孕妇的血液(BLL)和尿液(ULL)中的铅含量进行了评估,这些孕妇居住在拉各斯,并使用原子吸收光谱法进行了检测。对照组由 113 名未怀孕的女性组成。结果显示,孕妇的平均 BLL 和 ULL(μg/dL)分别为 59.5±2.1 和 29.4±1.1,明显高于未怀孕女性的 27.7±1.1 和 9.2±0.6(p<0.01)。第一、二、三孕期妇女的 BLL 分别为 57.2±2.3、61.6±2.2 和 63.1±1.8。由于相关性较弱(r=-0.06 至+0.15;p>0.10),ULL 不能用于预测 BLL。本研究为了解尼日利亚孕妇的血液和尿液铅含量做出了贡献,对于医疗保健管理、公共卫生决策和可能的初级预防活动具有重要意义。

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