Tata Institute of Fundamental Research, National Centre for Biological Sciences, Bangalore 560 065, India.
J Biosci. 2009 Oct;34(4):621-31. doi: 10.1007/s12038-009-0080-9.
Drosophila larvae can be trained to avoid odours associated with electric shock. We describe here, an improved method of aversive conditioning and a procedure for decomposing learning retention curve that enables us to do a quantitative analysis of memory phases, short term (STM), middle term (MTM) and long term (LTM) as a function of training cycles. The same method of analysis when applied to learning mutants dunce, amnesiac, rutabaga and radish reveals memory deficits characteristic of the mutant strains.
果蝇幼虫可以被训练回避与电击相关的气味。在这里，我们描述了一种改进的厌恶条件作用方法和一个用于分解学习保持曲线的程序，该方法使我们能够根据训练周期对记忆阶段（STM、MTM 和 LTM）进行定量分析。当将相同的分析方法应用于学习突变体 dunce、amnesiac、rutabaga 和 radish 时，会发现这些突变株具有记忆缺陷的特征。
