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2
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3
Distribution of resistant gram-positive organisms across the census regions of the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobial.美国各普查地区革兰氏阳性耐药菌的分布及新型甘氨酰环素类抗菌药物替加环素的体外活性
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遏制发展中国家的抗菌药物耐药性威胁。

Curbing the menace of antimicrobial resistance in developing countries.

作者信息

Nweneka Chidi Victor, Tapha-Sosseh Ndey, Sosa Anibal

机构信息

Medical Research Council Laboratories, Keneba Field Station, Banjul, The Gambia.

出版信息

Harm Reduct J. 2009 Nov 19;6:31. doi: 10.1186/1477-7517-6-31.

DOI:10.1186/1477-7517-6-31
PMID:19922676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2783017/
Abstract

Several reports suggest that antimicrobial resistance is an increasing global problem; but like most pandemics, the greatest toll is in the less developed countries. The dismally low rate of discovery of antimicrobials compared to the rate of development of antimicrobial resistance places humanity on a very dangerous precipice. Since antimicrobial resistance is part of an organism's natural survival instinct, total eradication might be unachievable; however, it can be reduced to a level that it no longer poses a threat to humanity. While inappropriate antimicrobial consumption contributes to the development of antimicrobial resistance, other complex political, social, economic and biomedical factors are equally important. Tackling the menace therefore should go beyond the conventional sensitization of members of the public and occasional press releases to include a multi-sectoral intervention involving the formation of various alliances and partnerships. Involving civil society organisations like the media could greatly enhance the success of the interventions.

摘要

几份报告表明,抗菌素耐药性是一个日益严重的全球性问题;但与大多数大流行病一样,受影响最严重的是欠发达国家。与抗菌素耐药性的发展速度相比,抗菌素的发现率低得可怜,这使人类处于非常危险的边缘。由于抗菌素耐药性是生物体自然生存本能的一部分,完全根除可能无法实现;然而,可以将其降低到不再对人类构成威胁的水平。虽然不适当的抗菌素消费助长了抗菌素耐药性的发展,但其他复杂的政治、社会、经济和生物医学因素同样重要。因此,应对这一威胁不应仅仅局限于对公众进行传统的宣传和偶尔发布新闻稿,还应进行多部门干预,包括组建各种联盟和伙伴关系。让媒体等民间社会组织参与进来,可以大大提高干预措施的成功率。