Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, China.
Genomics Proteomics Bioinformatics. 2009 Sep;7(3):143-6. doi: 10.1016/S1672-0229(08)60043-1.
Circular genomes, being the largest proportion of sequenced genomes, play an important role in genome analysis. However, traditional 2D circular map only provides an overview and annotations of genome but does not offer feature-based comparison. For remedying these shortcomings, we developed 3D Genome Tuner, a hybrid of circular map and comparative map tools. Its capability of viewing comparisons between multiple circular maps in a 3D space offers great benefits to the study of comparative genomics. The program is freely available (under an LGPL licence) at http://sourceforge.net/projects/dgenometuner.
环形基因组是测序基因组中最大的比例,在基因组分析中发挥着重要作用。然而,传统的二维环形图谱仅提供了基因组的概述和注释,但不能提供基于特征的比较。为了弥补这些不足,我们开发了 3D 基因组调谐器,这是一种环形图谱和比较图谱工具的混合体。它能够在 3D 空间中查看多个环形图谱之间的比较,这对比较基因组学的研究有很大的好处。该程序可在 http://sourceforge.net/projects/dgenometuner 免费获得(遵循 LGPL 许可证)。